Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Effect of combined diclofenac and B vitamins (thiamine, pyridoxine, and cyanocobalamin) for low back pain management: systematic review and meta-analysis

CA Calderon-Ospina, MO Nava-Mesa… - Pain …, 2020 - academic.oup.com
Background Cumulative evidence suggests an analgesic effect of thiamine, pyridoxine, and
cyanocobalamin (TPC) in monotherapy, and also when combined with nonsteroidal anti …

Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review

AM Paez-Hurtado, CA Calderon-Ospina… - Nutritional …, 2023 - Taylor & Francis
Pain is a complex sensory and emotional experience with nociceptive, nociplastic, and
neuropathic components. An involvement of neurotropic B vitamins (B1–thiamine, B6 …

[HTML][HTML] Mechanism of Action of Dihydroquercetin in the Prevention and Therapy of Experimental Liver Injury

H Wei, T Zhao, X Liu, Q Ding, J Yang, X Bi, Z Cheng… - Molecules, 2024 - mdpi.com
Liver disease is a global health problem that affects the well-being of tens of thousands of
people. Dihydroquercetin (DHQ) is a flavonoid compound derived from various plants …

[HTML][HTML] The effect of taxifolin on high-dose-cisplatin-induced oxidative liver injury in rats

N Kurt, ÖN Türkeri, B Suleyman… - Advances in Clinical …, 2021 - advances.umw.edu.pl
Background. Cisplatin is a non-specific platinum-based (derivative) chemotherapeutic agent
that causes an increase in free radicals activity in the liver. Antio xidant activity of taxifolin …

Effects of anakinra on the small intestine mucositis induced by methotrexate in rats

F Ozcicek, AV Kara, EM Akbas, N Kurt… - Experimental …, 2020 - jstage.jst.go.jp
Intestinal mucositis is an important problem in the patients receiving cancer treatment. We
aimed to investigate the effect of anakinra, which is a well known anti-oxidant and anti …

[HTML][HTML] Effect of thiamine pyrophosphate on cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats

M Ozer, S Ince, B Gundogdu, M Aktas… - Advances in clinical …, 2022 - advances.umw.edu.pl
Background. Cyclophosphamide is a drug used in various types of cancer. It can cause
oxidative and inflammatory ovarian damage and infertility. Thiamine pyrophosphate (TPP) to …

Anti-inflammatory and antioxidative effects of thiamin supplements in patients with gestational diabetes mellitus

E Amirani, E Aghadavod, R Shafabakhsh… - The Journal of …, 2022 - Taylor & Francis
Objective The aim of this study was to evaluate the effects of thiamin supplementation on
biomarkers of inflammation and oxidative stress in patients with gestational diabetes mellitus …

Metabolic Impact of Anticancer Drugs Pd2Spermine and Cisplatin on the Brain of Healthy Mice

TJ Carneiro, M Vojtek, S Gonçalves-Monteiro… - Pharmaceutics, 2022 - mdpi.com
The new palladium agent Pd2Spermine (Spm) has been reported to exhibit promising
cytotoxic properties, while potentially circumventing the known disadvantages associated to …

A metabolomic study on the gender-dependent effects of maternal exposure to fenvalerate on neurodevelopment in offspring mice

H Zhang, T Lu, Y Feng, X Sun, X Yang, K Zhou… - Science of the Total …, 2020 - Elsevier
Background The general population is widely exposed to fenvalerate. However, the effects
of maternal exposure to fenvalerate on neurodevelopment in offspring and the underlying …