[HTML][HTML] Stimuli-activatable nanomedicine meets cancer theranostics

H Li, Y Feng, Q Luo, Z Li, X Li, H Gan, Z Gu, Q Gong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …

Nanodelivery of cGAS-STING activators for tumor immunotherapy

J Guo, L Huang - Trends in Pharmacological Sciences, 2022 - cell.com
Activation of the cyclic guanosine monophosphate-adenosine monophosphate synthase
(cGAS)-stimulator of interferon genes (STING) pathway has great potential to promote …

Polymeric nanoparticle-based nanovaccines for cancer immunotherapy

Y Zhang, J Chen, L Shi, F Ma - Materials Horizons, 2023 - pubs.rsc.org
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …

Lymph node-targeting nanovaccines for cancer immunotherapy

Q Wang, Z Wang, X Sun, Q Jiang, B Sun, Z He… - Journal of Controlled …, 2022 - Elsevier
Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …

Stimuli-responsive polymeric nanovaccines toward next-generation immunotherapy

L Mao, P Ma, X Luo, H Cheng, Z Wang, E Ye, XJ Loh… - ACS …, 2023 - ACS Publications
The development of nanovaccines that employ polymeric delivery carriers has garnered
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …

Recent progress and applications of poly (beta amino esters)-based biomaterials

J Wei, L Zhu, Q Lu, G Li, Y Zhou, Y Yang… - Journal of Controlled …, 2023 - Elsevier
Poly (beta-amino esters, PBAEs) are a promising class of cationic polymers synthesized
from diacrylates and amines via Michael addition. Recently, PBAEs have been widely …

Nanomaterial-encapsulated STING agonists for immune modulation in cancer therapy

X Chen, Z Xu, T Li, A Thakur, Y Wen, K Zhang, Y Liu… - Biomarker …, 2024 - Springer
The cGAS-STING signaling pathway has emerged as a critical mediator of innate immune
responses, playing a crucial role in improving antitumor immunity through immune effector …

Force‐Triggered Self‐Destructive Hydrogels

T Rajasooriya, H Ogasawara, Y Dong… - Advanced …, 2023 - Wiley Online Library
Self‐destructive polymers (SDPs) are defined as a class of smart polymers that
autonomously degrade upon experiencing an external trigger, such as a chemical cue or …

[HTML][HTML] Recent advancements in immunotherapy of melanoma using nanotechnology-based strategies

A Bahreyni, Y Mohamud, H Luo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Melanoma is a malignant tumor that accounts for the deadliest form of skin cancers. Despite
the significant efforts made recently for development of immunotherapeutic strategies …

Nanoadjuvants actively targeting lymph node conduits and blocking tumor invasion in lymphatic vessels

H Liu, Z Wen, H Chen, Z Yang, Z Le, Z Liu… - Journal of Controlled …, 2022 - Elsevier
Great efforts have been made to manipulate nanoparticles (NPs) with a diameter of 10–100
nm to passively target lymph nodes (LNs) to magnitude anti-tumor activity of T cells …