[HTML][HTML] Stimuli-activatable nanomedicine meets cancer theranostics
Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …
Nanodelivery of cGAS-STING activators for tumor immunotherapy
Activation of the cyclic guanosine monophosphate-adenosine monophosphate synthase
(cGAS)-stimulator of interferon genes (STING) pathway has great potential to promote …
(cGAS)-stimulator of interferon genes (STING) pathway has great potential to promote …
Polymeric nanoparticle-based nanovaccines for cancer immunotherapy
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
Lymph node-targeting nanovaccines for cancer immunotherapy
Q Wang, Z Wang, X Sun, Q Jiang, B Sun, Z He… - Journal of Controlled …, 2022 - Elsevier
Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …
Stimuli-responsive polymeric nanovaccines toward next-generation immunotherapy
The development of nanovaccines that employ polymeric delivery carriers has garnered
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …
Recent progress and applications of poly (beta amino esters)-based biomaterials
J Wei, L Zhu, Q Lu, G Li, Y Zhou, Y Yang… - Journal of Controlled …, 2023 - Elsevier
Poly (beta-amino esters, PBAEs) are a promising class of cationic polymers synthesized
from diacrylates and amines via Michael addition. Recently, PBAEs have been widely …
from diacrylates and amines via Michael addition. Recently, PBAEs have been widely …
Nanomaterial-encapsulated STING agonists for immune modulation in cancer therapy
X Chen, Z Xu, T Li, A Thakur, Y Wen, K Zhang, Y Liu… - Biomarker …, 2024 - Springer
The cGAS-STING signaling pathway has emerged as a critical mediator of innate immune
responses, playing a crucial role in improving antitumor immunity through immune effector …
responses, playing a crucial role in improving antitumor immunity through immune effector …
Force‐Triggered Self‐Destructive Hydrogels
T Rajasooriya, H Ogasawara, Y Dong… - Advanced …, 2023 - Wiley Online Library
Self‐destructive polymers (SDPs) are defined as a class of smart polymers that
autonomously degrade upon experiencing an external trigger, such as a chemical cue or …
autonomously degrade upon experiencing an external trigger, such as a chemical cue or …
[HTML][HTML] Recent advancements in immunotherapy of melanoma using nanotechnology-based strategies
Melanoma is a malignant tumor that accounts for the deadliest form of skin cancers. Despite
the significant efforts made recently for development of immunotherapeutic strategies …
the significant efforts made recently for development of immunotherapeutic strategies …
Nanoadjuvants actively targeting lymph node conduits and blocking tumor invasion in lymphatic vessels
Great efforts have been made to manipulate nanoparticles (NPs) with a diameter of 10–100
nm to passively target lymph nodes (LNs) to magnitude anti-tumor activity of T cells …
nm to passively target lymph nodes (LNs) to magnitude anti-tumor activity of T cells …