[PDF][PDF] The role of nitric oxide in health and diseases

M Khazan, M Hedayati - Scimetr, 2015 - brieflands.com
: Context: Nitric oxide (NO) is a free radical and synthesized by three Nitric Oxide isoforms.
NO is a biological messenger with many important effects on variety of biological processes …

Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal …

AS Awad, R Kamel, MAE Sherief - Journal of pharmacy and …, 2011 - academic.oup.com
Objectives Renal ischaemia–reperfusion (I/R) is a well-characterised model of acute renal
failure that causes both local and remote organ injury. The aim of this work was to …

Downregulation of glutathione biosynthesis contributes to oxidative stress and liver dysfunction in acute kidney injury

Y Shang, YL Siow, CK Isaak, KO - Oxidative Medicine and …, 2016 - Wiley Online Library
Ischemia‐reperfusion is a common cause for acute kidney injury and can lead to distant
organ dysfunction. Glutathione is a major endogenous antioxidant and its depletion directly …

Thymoquinone improves the kidney and liver changes induced by chronic cyclosporine A treatment and acute renal ischaemia/reperfusion in rats

MM Farag, GO Ahmed, RR Shehata… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives This study was designed to evaluate the effects of chronic cyclosporine A (CsA)
treatment and acute renal ischaemia/reperfusion (I/R) on the kidney and liver in …

Effects of putrescine on oxidative stress, spermidine/spermine-N (1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia …

D Dasdelen, N Cetin, E Menevse, AK Baltaci… - Physiology …, 2023 - akjournals.com
We aimed to examine the effects of brain ischemia-reperfusion (IR) especially on serum
parameters or liver enzymes, free radicals, cytokines, oxidatively damaged DNA …

TLR9 mediates remote liver injury following severe renal ischemia reperfusion

PJ Bakker, AM Scantlebery, LM Butter, N Claessen… - PloS one, 2015 - journals.plos.org
Ischemia reperfusion injury is a common cause of acute kidney injury and is characterized
by tubular damage. Mitochondrial DNA is released upon severe tissue injury and can act as …

Gut derived-endotoxin contributes to inflammation in severe ischemic acute kidney injury

J Li, KR Moturi, L Wang, K Zhang, C Yu - BMC nephrology, 2019 - Springer
Background Recent researches indicate that the intestinal consequences of renal ischemia
reperfusion (IR) would predispose to the translocation of gut-derived endotoxin. Here, we …

[HTML][HTML] Vagus nerve stimulation protects against acute liver injury induced by renal ischemia reperfusion via antioxidant stress and anti-inflammation

Y Lai, J Deng, M Wang, M Wang, L Zhou… - Biomedicine & …, 2019 - Elsevier
Objective Renal ischemia reperfusion (I/R) is not an isolated event; however, it results in
remote organ dysfunction. Vagus nerve stimulation (VNS) has shown protective effects …

[PDF][PDF] Oxytocin ameliorates remote liver injury induced by renal ischemia-reperfusion in rats

AT Hekimoglu, G Toprak, H Akkoc… - The Korean Journal …, 2013 - synapse.koreamed.org
Renal ischemia-reperfusion (IR) causes remote liver damage. Oxytocin has anti-
inflammatory and antioxidant effects. The main purpose of this study was to evaluate the …

Prostaglandin-E1 has a protective effect on renal ischemia/reperfusion-induced oxidative stress and inflammation mediated gastric damage in rats

S Gezginci-Oktayoglu, N Orhan, S Bolkent - International …, 2016 - Elsevier
Gastrointestinal complications are frequent in renal transplant recipients. In this regard, renal
ischemia/reperfusion injury (IRI)-induced gastric damage seems to be important and there is …