Recent advancement in synthesis and bioactivities of 1, 3, 4-oxadiazole
T Chaudhary, PK Upadhyay - Current Organic Synthesis, 2023 - benthamdirect.com
Derivatives of 1, 3, 4-oxadiazole are effective in the treatment and cure of a wide range of
diseases in medical chemistry, while industrial development has shown that they can be …
diseases in medical chemistry, while industrial development has shown that they can be …
New Ni (II) and Pd (II) complexes bearing derived sulfa drug ligands: synthesis, characterization, DFT calculations, and in silico and in vitro biological activity studies
MA Bourouai, K Si Larbi, A Bouchoucha… - Biometals, 2023 - Springer
In the present study, the synthesis of six new Ni (II) and Pd (II) complexes with three derived
sulfamethoxazole drug ligands is reported. The coordination mode, geometry, and chemical …
sulfamethoxazole drug ligands is reported. The coordination mode, geometry, and chemical …
New Copper Complexes with Antibacterial and Cytotoxic Activity
The discovery of a new non-toxic metal complex with biological activity represents a very
active area of research. Two Cu+ 2 complexes,[Cu4 (L1) 4 (OH) 4 (DMF) 2 (H2O)](C1)(HL1 …
active area of research. Two Cu+ 2 complexes,[Cu4 (L1) 4 (OH) 4 (DMF) 2 (H2O)](C1)(HL1 …
Synthesis, spectral characterization of pyrazole derived Schiff base analogs: molecular dynamic simulation, antibacterial and DNA binding studies
We have synthesized the pyrazole-bearing Schiff base derivatives (5a–5e) and (6a–6h) then
the structural confirmation was supported by various spectral analyses. The antibacterial …
the structural confirmation was supported by various spectral analyses. The antibacterial …
Recent Updates on Interaction Studies and Drug Delivery of Antimalarials with Serum Albumin proteins
This review focuses on recent trends in the binding study of various antimalarial agents with
serum albumins in detail. Serum albumin has a significant role in the transport of drugs and …
serum albumins in detail. Serum albumin has a significant role in the transport of drugs and …
Phytochemical and antibacterial analysis of Pistacia integerrima: An integrated in vitro and in silico approach
Antibiotic resistance is a global concern due to the ability of bacteria to continuously develop
various mechanisms of resistance against diverse antimicrobial classes; therefore, there is a …
various mechanisms of resistance against diverse antimicrobial classes; therefore, there is a …
Pd-catalyzed synthesis, characterization, and biological evaluations of pyrazole derivatives: DFT, molecular modelling and antioxidant studies
Abstract Using Pd (PPh 3) 4 as a catalyst, a new series of coupling products (5a–5l)
synthesized from pyrazole derivatives (4a-4c) and substituted boronic acids. Afterward, 1 H …
synthesized from pyrazole derivatives (4a-4c) and substituted boronic acids. Afterward, 1 H …
Design, synthesis and Mechanistic studies of novel isatin-Pyrazole Hydrazone conjugates as selective and potent Bacterial MetAP inhibitors
Methionine aminopeptidases (MetAPs) are attractive drug targets due to their essential role
in eukaryotes as well as prokaryotic cells. In this study, biochemical assays were performed …
in eukaryotes as well as prokaryotic cells. In this study, biochemical assays were performed …
Target-based virtual screening of natural compounds identifies a potent antimalarial with selective falcipain-2 inhibitory activity
A Uddin, S Gupta, T Mohammad, D Shahi… - Frontiers in …, 2022 - frontiersin.org
We employed a comprehensive approach of target-based virtual high-throughput screening
to find potential hits from the ZINC database of natural compounds against cysteine …
to find potential hits from the ZINC database of natural compounds against cysteine …
Acrylonitrile adducts: design, synthesis and biological evaluation as antimicrobial, haemolytic and thrombolytic agent
In this work, five acrylonitrile adducts were screened for antibacterial activity against Gram-
positive Bacillus subtilis, Microbial Type Culture Collection and Gene Bank (MTCC 1305) …
positive Bacillus subtilis, Microbial Type Culture Collection and Gene Bank (MTCC 1305) …