[HTML][HTML] Differential Protein Expression in Extracellular Vesicles Defines Treatment Responders and Non-Responders in Multiple Sclerosis

G Torres Iglesias, MP López-Molina, L Botella… - International Journal of …, 2024 - mdpi.com
Multiple sclerosis (MS) remains the leading cause of neurological disability among young
adults worldwide, underscoring the urgent need to define the best therapeutic strategy …

Establishment of the Diagnostic Signature of Ferroptosis Genes in Multiple Sclerosis

Y Yang, Q Bai, F Liu, S Zhang, W Tang, L Liu… - Biochemical …, 2024 - Springer
Ferroptosis is a novel form of membrane-dependent cell death that differs from other cell
death modalities such as necrosis, apoptosis, and autophagy. Multiple sclerosis (MS) is a …

Interaction between Ras and Bcl2L12 in B cells suppresses IL-10 expression

J Li, G Yang, XQ Luo, LH Mo, SY Qiu, LT Yang… - Clinical …, 2021 - Elsevier
The pathogenesis of recurrent tonsillitis is to be further investigated. B cell-derived
interleukin (IL)-10 plays a critical role in immune regulation. Ras activation plays an …

CD40 induces selective routing of Ras isoforms to subcellular compartments

A Nair, S Chakraborty, B Saha - Journal of Cell Communication and …, 2023 - Springer
Ras GTPases are central to cellular signaling and oncogenesis. The three loci of the Ras
gene encode for four protein isoforms namely Harvey-Ras (H-Ras), Kirsten-Ras (K-Ras 4A …

The farnesyltransferase inhibitor tipifarnib protects against autoimmune hepatitis induced by Concanavalin A

J Guo, K Shirozu, T Akahoshi, Y Mizuta… - International …, 2020 - Elsevier
No effective treatment has been established for autoimmune hepatitis (AIH), except for liver
transplantation in the fatal stage. Little is known about the roles and mechanisms of …

Identification of Arl13b GTPase-activating proteins towards the impairment of tumor progression

IMC Ferreira - 2018 - search.proquest.com
Cancer metastasis relies on cancer cell migration and invasion of tissues surrounding the
primary tumor and is the leading cause of cancer-related deaths. Our group previously …