Polypyrimidine tract‐binding protein (PTB), as a member of the heterogeneous nuclear
ribonucleoprotein family, functions by rapidly shuttling between the nucleus and the …

Apoptosis, a major hallmark of cancer cells, regulates cellular fate and homeostasis. BCL-2
(B-cell CLL/Lymphoma 2) protein family is popularly known to mediate the intrinsic mode of …

Background Hypoxic tumors are refractory to DNA damage drugs. However, the underlying
mechanism has yet to be elucidated. We aimed to identify lncRNAs that upregulated under …

Long noncoding RNA (lncRNA) represents a class of endogenous RNAs that regulate gene
expression in eukaryotes. To date, the function and underlying mechanism of the majority of …

Chemoresistance is the main obstacle of treatment in patients with osteosarcoma. RNA‐
binding protein PTBP1 has been identified as an oncogene in various cancers. However …

The lncRNA SNHG6 (small nucleolar RNA host gene 6) plays vital roles in tumorigenesis
and the progression of hepatocellular carcinoma (HCC). However, the regulatory …

Deadenylation‐dependent mRNA decapping and decay is the major cytoplasmic mRNA
turnover pathway in eukaryotes. Many mRNA decapping and decay factors are associated …

Gene expression is tightly regulated at the levels of both mRNA translation and stability. The
poly (A)‐binding protein (PABP) is thought to play a role in regulating these processes by …

Background Although anti-apoptotic proteins of the B-cell lymphoma-2 (BCL2) family have
been utilized as therapeutic targets in acute myeloid leukaemia (AML), their complicated …

MicroRNAs (miRNAs) and RNA-binding proteins (RBPs) are important regulators of mRNA
translation and stability in eukaryotes. While miRNAs can only bind their target mRNAs in …