Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …

Advances in the technologic armamentarium available to basic and clinical investigators
have enabled increasingly sophisticated studies of brain function in health and disease. This …

Bipolar disorder (also known as manic depressive illness) is a complex genetic disorder in
which the core feature is pathological disturbance in mood (affect) ranging from extreme …

Using genotypes from nearly 8,000 short tandem-repeat polymorphisms typed in eight of the
reference families from the Centre d'Étude du Polymorphisme Humain (CEPH), we identified …

Wilson disease (WD) is an autosomal recessive disorder characterized by toxic
accumulation of copper in the liver and subsequently in the brain and other organs. On the …

▪ Abstract Human behavioral genetic research aimed at characterizing the existence and
nature of genetic and environmental influences on individual differences in cognitive ability …

Schizophrenic and bipolar disorders are similar in several epidemiologic respects, including
age at onset, lifetime risk, course of illness, worldwide distribution, risk for suicide, gender …

Bipolar disorder is a severe mental illness characterized by mood swings of elation and
depression. Family, twin, and adoption studies suggest a complex genetic etiology that may …

The search for genes in bipolar disorder has provided numerous genetic loci that have been
linked to susceptibility to developing the disorder. However, because of the genetic …

Bipolar disorder (BP) is a complex disorder caused by a number of liability genes interacting
with the environment. In recent years, a large number of linkage and association studies …