The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering
RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …

Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …

Although high-throughput RNA sequencing (RNA-seq) has greatly advanced small non-
coding RNA (sncRNA) discovery, the currently widely used complementary DNA library …

Summary tRNA function is based on unique structures that enable mRNA decoding using
anticodon trinucleotides. These structures interact with specific aminoacyl-tRNA synthetases …

Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …

Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are among the most ancient small RNAs
in all domains of life and are generated by the cleavage of tRNAs. Emerging studies have …

Recent advancements in small RNA sequencing have unveiled a previously hidden world of
regulatory small noncoding RNAs (sncRNAs) that extend beyond the well-studied small …

Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

Since the discovery of the first miRNA in 1993, numerous studies have focused on their
biogenesis, their functions on regulating a diversity of cellular processes, and the molecular …

A new class of noncoding RNAs, tsRNAs are not only abundant in humans but also have
high tissue specificity. Recently, an increasing number of studies have explored the …