Pharmacological potential of betulin as a multitarget compound

FO Adepoju, KC Duru, E Li, EG Kovaleva, MV Tsurkan - Biomolecules, 2023 - mdpi.com
Betulin is a natural triterpene, usually from birch bark, known for its potential wound-healing
properties. Despite having a wide range of pharmacological targets, no studies have …

Antidiabetic plant-derived nutraceuticals: a critical review

J Naveen, V Baskaran - European journal of nutrition, 2018 - Springer
Diabetes mellitus (DM) is one of the major health problems in the world, especially amongst
the urban population. Chemically synthesized drugs used to decrease the ill effects of DM …

The effects of bioactive compounds from blueberry and blackcurrant powders on the inhibitory activities of oat bran pastes against α-amylase and α-glucosidase linked …

X Hui, G Wu, D Han, L Stipkovits, X Wu, S Tang… - Food Research …, 2020 - Elsevier
The α-amylase and α-glucosidase inhibitory activities by extracts of oat bran, blueberry and
blackcurrant powders, as well as oat bran pastes supplemented 25% of blueberry and …

Phytochemical screening, in vitro anti-oxidant activity, and in silico anti-diabetic activity of aqueous extracts of Ruellia tuberosa L

A Safitri, F Fatchiyah, DRT Sari… - Journal of Applied …, 2020 - japsonline.com
The study aimed to investigate the phytochemical profiles, in vitro antioxidant activity, and in
silico molecular docking antidiabetic activity of the aqueous root extracts of Ruellia tuberosa …

[PDF][PDF] Antioxidant and antidiabetic potential of Curcuma longa and its compounds.

W Widowati, TL Wargasetia, E Afifah, T Mozef… - 2018 - asianjab.com
Antioxidant agent can eliminate the free radicals due to oxidative stress that has been
reported as the main cause of diabetes mellitus. This study evaluated the effect of Curcuma …

Protective Effect of Betulin on Streptozotocin–Nicotinamide-Induced Diabetes in Female Rats

FO Adepoju, KV Sokolova, IF Gette… - International Journal of …, 2024 - mdpi.com
Type 2 diabetes is characterized by hyperglycemia and a relative loss of β–cell function. Our
research investigated the antidiabetic potential of betulin, a pentacyclic triterpenoid found …

Incredible affinity of Kattosh with PPAR‐γ receptors attenuates STZ‐induced pancreas and kidney lesions evidenced in chemicobiological interactions

MM Rashid, MA Rahman, MS Islam… - Journal of Cellular …, 2022 - Wiley Online Library
Since ancient times, plants have been used as green bioresources to ensure a healthier life
by recovering from different diseases. Kattosh (Lasia spinosa L. Thwaites) is a local plant …

Identification of α-amylase inhibitory compounds from leaves of Careya arborea Roxb. and in silico docking studies

RP Kamble, P Ghosh, AA Kulkarni - South african journal of botany, 2022 - Elsevier
Abstract Diabetes mellitus Type 2 (DM 2) is a lifestyle induced metabolic disease
characterized by chronic hyperglycaemia, dyslipidaemia and impaired protein metabolism …

Identification of Bioactive Components from Ruellia tuberosa L. on Improving Glucose Uptake in TNF‐α‐Induced Insulin‐Resistant Mouse FL83B Hepatocytes

JH Xu, YM Lo, WC Chang, DW Huang… - Evidence‐Based …, 2020 - Wiley Online Library
Ruellia tuberosa L.(RTL) has been used as a folk medicine to cure diabetes in Asia. RTL
was previously reported to alleviate hyperglycemia, insulin resistance (IR), abnormal hepatic …

Design, Synthesis and biological evaluation of novel benzopyran derivatives as potential α-amylase inhibitors: An Investigation by Experimental and Computational …

A Hajlaoui, A Assel, H Lazrag, J Bouajila… - Journal of Molecular …, 2023 - Elsevier
A novel series of benzopyran derivatives 4, 5, and 6a-i was synthesized via
cyclocondensation reaction of hydrazide 3 with some electrophilic species such as 2, 4 …