[HTML][HTML] The role of immune cells in breast tissue and immunotherapy for the treatment of breast cancer

SL Goff, DN Danforth - Clinical breast cancer, 2021 - Elsevier
Immune cells are present in normal breast tissue and in breast carcinoma. The nature and
distribution of the immune cell subtypes in these tissues are reviewed to promote a better …

The immune microenvironment of breast cancer progression

H Tower, M Ruppert, K Britt - Cancers, 2019 - mdpi.com
Inflammation is now recognized as a hallmark of cancer. Genetic changes in the cancer cell
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …

The immune microenvironment and cancer metastasis

A El-Kenawi, K Hänggi… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
The dynamic interplay between neoplastic cells and the immune microenvironment
regulates every step of the metastatic process. Immune cells contribute to invasion by …

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

KL Gorringe, SB Fox - Frontiers in oncology, 2017 - frontiersin.org
Ductal carcinoma in situ (DCIS) is an often-diagnosed breast disease and a known, non-
obligate, precursor to invasive breast carcinoma. In this review, we explore the clinical and …

Ductal carcinoma in situ of breast: update 2019

SS Badve, Y Gökmen-Polar - Pathology, 2019 - Elsevier
Ductal carcinoma in situ is a non-invasive form of breast cancer. Its incidence is increasing
due to widespread use of mammographic screening. It presents several diagnostic and …

[HTML][HTML] Everybody needs good neighbours: the progressive DCIS microenvironment

SV Gibson, RM Roozitalab, MD Allen, JL Jones… - Trends in cancer, 2023 - cell.com
Ductal carcinoma in situ (DCIS) is a pre-invasive form of breast cancer where neoplastic
luminal cells are confined to the ductal tree. While as many as 70% of DCIS cases will …

[HTML][HTML] Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast

MS Toss, I Miligy, A Al-Kawaz, M Alsleem, H Khout… - Modern Pathology, 2018 - Elsevier
Tumor-infiltrating lymphocytes (TILs) provide prognostic value in invasive breast cancer and
guidelines for their assessment have been published. This study aims to evaluate:(a) …

Prognostic significance of tumour‑infiltrating lymphocytes for oestrogen receptor‑negative breast cancer without lymph node metastasis

S Kurozumi, H Matsumoto, M Kurosumi… - Oncology …, 2019 - spandidos-publications.com
Tumour‑infiltrating lymphocytes (TILs) are regarded as significant prognostic markers in
patients with breast cancer. However, the prognostic utility of TIL expression based on the …

Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System

A Trinh, CR Gil Del Alcazar, SA Shukla, K Chin… - Molecular Cancer …, 2021 - AACR
The drivers of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) transition
are poorly understood. Here, we conducted an integrated genomic, transcriptomic, and …

Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk

MM Almekinders, T Bismeijer, T Kumar, F Yang… - British journal of …, 2022 - nature.com
Background Ductal carcinoma in situ (DCIS) is treated to prevent subsequent ipsilateral
invasive breast cancer (iIBC). However, many DCIS lesions will never become invasive. To …