Mossy cells comprise a large fraction of the cells in the hippocampal dentate gyrus,
suggesting that their function in this region is important. They are vulnerable to ischaemia …

“Ca2+ buffers,” a class of cytosolic Ca2+-binding proteins, act as modulators of short-lived
intracellular Ca2+ signals; they affect both the temporal and spatial aspects of these …

Gene-targeted mice lacking thel-α-amino-3-hydroxy-5-methylisoxazole-4-propionate
(AMPA) receptor subunit GluR-A exhibited normal development, life expectancy, and fine …

Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is
bound to buffers, with typically only∼ 1% being freely ionized at resting levels in most cells …

We here show that the early postmitotic stage of granule cell development during adult
hippocampal neurogenesis is characterized by the transient expression of calretinin (CR) …

The notion that changes in synaptic efficacy underlie learning and memory processes is now
widely accepted, although definitive proof of the synaptic plasticity and memory hypothesis …

Abstract Calretinin (CR), calbindin D-28k (CB) and parvalbumin (PV) belong to the large
family of EF-hand calcium-binding proteins, which comprises more than 200 members in …

The three calcium-binding proteins parvalbumin, calbindin, and calretinin are found in
morphologically distinct classes of inhibitory interneurons as well as in some pyramidal …

Post-translational epigenetic modifications take place in mouse neurons of the dentate gyrus
(DG) with age. Here, we report that age-dependent reduction in H3K9 trimethylation …

Despite this effort, a widely accepted and satisfying molecular explanation for LTP has not
yet been discovered or, at least, been generally accepted. Rather, at least to outsiders, it …