Plassembler: an automated bacterial plasmid assembly tool

G Bouras, AE Sheppard, V Mallawaarachchi… - …, 2023 - academic.oup.com
With recent advances in sequencing technologies, it is now possible to obtain near-perfect
complete bacterial chromosome assemblies cheaply and efficiently by combining a long …

Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

O Xie, JM Morris, AJ Hayes, RJ Towers… - Nature …, 2024 - nature.com
Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human
infection with invasive disease incidence and clinical manifestations comparable to the …

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

J Schwarzerova, A Labanava, I Rychlik… - Frontiers in …, 2023 - frontiersin.org
The horizontal transfer of mobile gene elements between bacteria plays a crucial role in
their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of …

Applying rearrangement distances to enable plasmid epidemiology with pling

D Frolova, L Lima, LW Roberts… - Microbial …, 2024 - microbiologyresearch.org
Plasmids are a key vector of antibiotic resistance, but the current bioinformatics toolkit is not
well suited to tracking them. The rapid structural changes seen in plasmid genomes present …

Global genomic epidemiology of blaGES-5 carbapenemase-associated integrons

W Matlock, LP Shaw, N Stoesser - Microbial Genomics, 2024 - microbiologyresearch.org
Antimicrobial resistance (AMR) gene cassettes comprise an AMR gene flanked by short
recombination sites (attI and attC or attC and attC). Integrons are genetic elements able to …

Plasmid-driven strategies for clone success in Escherichia coli

S Arredondo-Alonso, AK Pöntinen, JA Gama… - bioRxiv, 2023 - biorxiv.org
Escherichia coli is a major human pathogen and the most widely studied microbe in history,
but its extrachromosomal elements known as plasmids remain poorly delineated. Here we …

High-Risk Lineages of Hybrid Plasmids Carrying Virulence and Carbapenemase Genes

VV Shapovalova, PS Chulkova, VA Ageevets… - Antibiotics, 2024 - mdpi.com
Background/Objectives: Carbapenem-resistant Enterobacterales (CRE) are a global health
threat due to their high morbidity and mortality rates and limited treatment options. This study …

Анализ плазмид комплекса Klebsiella pneumoniae, несущих кластер генов синтеза аэробактина, представленных в международных базах данных

ВВ Шаповалова, ПС Чулкова… - Антибиотики и …, 2023 - antibiotics-chemotherapy.ru
Аннотация Введение. На данный момент принято выделять два патотипа Klebsiella
pneumoniae—классические и гипервирулентные, обладающие способностью вызывать …