Childhood nephrotic syndromes are most commonly caused by one of two idiopathic
diseases: minimal-change nephrotic syndrome (MCNS) and focal segmental …

All forms of primary GN may recur after kidney transplantation and potentially jeopardize the
survival of the graft. IgA nephritis (IgAN) may recur in approximately one third of patients …

Overexpression of soluble urokinase receptor (suPAR) causes pathology in animal models
similar to primary FSGS, and one recent study demonstrated elevated levels of serum …

NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic
syndrome and low post-transplant recurrence. Background Mutations of NPHS2 are …

Several genes have been implicated in genetic forms of nephrotic syndrome occurring in
children. It is now known that the phenotypes associated with mutations in these genes …

Idiopathic NS (nephrotic syndrome) is characterized by massive proteinuria, due to a leak in
the glomerular barrier to proteins. Genetic defects that affect the function and the …

A total of 179 children with sporadic nephrotic syndrome were screened for podocin
mutations: 120 with steroid resistance, and 59 with steroid dependence/frequent relapses …

Focal segmental glomerular sclerosis (FSGS) is a pathological term to indicate glomerular
lesions associated with distinctive clinical features. In most cases, FSGS is primary in nature …

Recurrent focal segmental glomerulosclerosis (FSGS) following transplantation is ascribed
to the presence of a circulating FSGS permeability factor (FSPF). Plasmapheresis (PP) can …

Background Evidence on the role of plasma exchange for treating recurrent post-transplant
focal segmental glomerulosclerosis (FSGS) comes largely from individual cases and …