Genetic and genomic studies have enhanced our understanding of complex
neurodegenerative diseases that exert a devastating impact on individuals and society. One …

Age‐related macular degeneration (AMD) is a progressive degenerative disease that is the
leading cause of vision loss in the elderly population. Degeneration/dysregulation of the …

Regional phenotypic and functional differences in the retinal pigment epithelium (RPE)
monolayer have been suggested to account for regional susceptibility in ocular diseases …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
elderly people globally. It is estimated that there will be more Asians with AMD than the rest …

For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Age-related macular degeneration (AMD) is the most frequent cause of irreversible
blindness in the elderly in developed countries. Our previous studies implicated activation of …

Bruch's membrane (BM) is a unique pentalaminar structure, which is strategically located
between the retinal pigment epithelium (RPE) and the fenestrated choroidal capillaries of …

Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

Age-related macular degeneration (AMD) is a multifactorial disease influenced by a
combination of environmental factors and genetic variants. Genomic studies have been …

Today, the average life expectancy in developed nations is over 80 years and climbing. And
yet, the quality of life during those additional years is often significantly diminished by the …