The gastrointestinal (GI) system contains many different types of immune cells, making it a
key immune organ system in the human body. In the last decade, our knowledge has …

Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …

Barrier integrity is central to the maintenance of healthy immunological homeostasis.
Impaired skin barrier function is linked with enhanced allergen sensitization and the …

The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting
the role of a disturbed interaction between the gut and the intestinal microbiota. A defective …

The gastrointestinal tract is a mucosal surface constantly exposed to foreign antigens and
microbes, and is protected by a vast array of immunologically active structures and cells …

Butyrate production in the large intestine and ruminant forestomach depends on bacterial
butyryl‐CoA/acetate‐CoA transferase activity and is highest when fermentable fiber and …

Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are
inflammatory disorders caused by multiple factors. Research on IBD has often used the …

Mucus is a complex hydrogel that acts as a natural barrier to drug delivery at different
mucosal surfaces including the respiratory, gastrointestinal, and vaginal tracts. To elucidate …

Background Inflammatory bowel diseases (IBD), including mainly ulcerative colitis (UC) and
Crohn's disease (CD), are inflammatory disorders of the gastrointestinal tract caused by an …

BACKGROUND: Inflammatory bowel disease (IBD) is associated with increased intestinal
permeability and decreased expression of tight junction (TJ) proteins in the inflamed …