EMT-induced immune evasion: connecting the dots from mechanisms to therapy

SO Imodoye, KA Adedokun - Clinical and Experimental Medicine, 2023 - Springer
Epithelial–mesenchymal transition (EMT) is a dynamic program crucial for organismal
development and tissue regeneration. Unfortunately, this program is often hijacked by …

KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir

A Astorga-Gamaza, D Perea, N Sanchez-Gaona… - Cell Reports …, 2023 - cell.com
Human immunodeficiency virus (HIV) infection induces immunological dysfunction, which
limits the elimination of HIV-infected cells during treated infection. Identifying and targeting …

The role of KLRG1: a novel biomarker and new therapeutic target

Y Zhang, S Chen, X Tang, Y Peng, T Jiang… - Cell Communication and …, 2024 - Springer
Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor expressed
predominantly in NK and T-cell subsets that downregulates the activation and proliferation of …

Active juvenile systemic lupus erythematosus is associated with distinct NK cell transcriptional and phenotypic alterations

A Radziszewska, H Peckham, NM de Gruijter… - Scientific Reports, 2024 - nature.com
While adaptive immune responses have been studied extensively in SLE (systemic lupus
erythematosus), there is limited and contradictory evidence regarding the contribution of …

Increased ILT2+ natural killer T cells correlate with disease activity in systemic lupus erythematosus

N Chen, Y Dai, H Li, X Long, J Ke, J Zhang, H Sun… - Clinical …, 2023 - Springer
Objective Numerous immune cell types, such as B and T lymphocytes, natural killer cells
(NK), and NKT cells, are related to the pathogenesis of diseases in systemic lupus …