ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[HTML][HTML] 18F-labeled, PSMA-targeted radiotracers: leveraging the advantages of radiofluorination for prostate cancer molecular imaging

RA Werner, T Derlin, C Lapa, S Sheikbahaei… - Theranostics, 2020 - ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA)-targeted PET imaging for prostate cancer with
68 Ga-labeled compounds has rapidly become adopted as part of routine clinical care in …

First-in-humans study of the SSTR antagonist 177Lu-DOTA-LM3 for peptide receptor radionuclide therapy in patients with metastatic neuroendocrine neoplasms …

RP Baum, J Zhang, C Schuchardt… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The objective of this study was to assess the safety, dosimetry, and efficacy of the 177Lu-
labeled somatostatin receptor (SSTR) antagonist DOTA-p-Cl-Phe-cyclo (d-Cys-Tyr-d-4 …

Theranostic advances in breast cancer in nuclear medicine

N Vahidfar, A Aghanejad, H Ahmadzadehfar… - International journal of …, 2021 - mdpi.com
The implication of 'theranostic'refers to targeting an identical receptor for diagnostic and
therapeutic purposes, by the same radioligand, simultaneously or separately. In regard to …

Prognostic value of 18F-FDG PET/CT in a large cohort of patients with advanced metastatic neuroendocrine neoplasms treated with peptide receptor radionuclide …

J Zhang, Q Liu, A Singh, C Schuchardt… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The objective of this retrospective study was to determine the role of 18F-FDG PET/CT in a
large cohort of 495 patients with metastatic neuroendocrine neoplasms (NENs) who were …

Application of machine learning to pretherapeutically estimate dosimetry in men with advanced prostate cancer treated with 177Lu-PSMA I&T therapy

S Xue, A Gafita, C Dong, Y Zhao, G Tetteh… - European journal of …, 2022 - Springer
Purpose Although treatment planning and individualized dose application for emerging
prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) are …

Peptide Receptor Radionuclide Therapy with [177Lu]Lu-DOTA-TATE in Patients with Advanced GEP NENS: Present and Future Directions

MI del Olmo-García, S Prado-Wohlwend, P Bello… - Cancers, 2022 - mdpi.com
Simple Summary Neuroendocrine neoplasms have been usually described as infrequent
tumors, but their incidence has been rising over time.[177Lu] Lu-DOTA-TATE (PRRT-Lu) …

Theranostic implications of molecular imaging phenotype of well-differentiated pulmonary carcinoid based on 68Ga-DOTATATE PET/CT and 18F-FDG PET/CT

L Zidan, A Iravani, G Kong, T Akhurst, M Michael… - European Journal of …, 2021 - Springer
Purpose This study aimed to analyse the molecular imaging (MI) phenotype of typical
carcinoid (TC) and atypical carcinoid (AC) by 68 Ga-DOTATATE (GaTATE) and 18 F-FDG …

[HTML][HTML] Ovarian cancer targeted theranostics

S Nimmagadda, MF Penet - Frontiers in oncology, 2020 - frontiersin.org
Ovarian cancer is a leading cause of death from gynecological malignancies. Although the
prognosis is quite favorable if detected at an early stage, the vast majority of cases are …

Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake

RA Werner, RA Bundschuh, L Bundschuh… - Molecular imaging and …, 2020 - Springer
Purpose In this study, we aimed to quantitatively investigate the biodistribution of [18 F]
DCFPyL in patients with prostate cancer (PCa) and to determine whether uptake in normal …