Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Infection with the malaria parasite, Plasmodium, is characterized by excessive inflammation.
The establishment of a precise balance between the pro-and anti-inflammatory responses is …

The transcription factor forkhead box protein 3 (FOXP3) is an essential molecular marker of
regulatory T cell (Treg) development in different microenvironments. Tregs are cells …

Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …

Parasitology Highly detailed textbook on parasites and parasite relationships The fully
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …

Infectious agents have intimately co-evolved with the host immune system, acquiring a
portfolio of highly sophisticated mechanisms to modulate immunity. Among the common …

Background During malaria infection, multiple pro-inflammatory mediators including IFN-γ,
TNF and nitric oxide (NO) play a crucial role in the protection against the parasites …

Population studies show that individuals acquire immunity to Plasmodium vivax more
quickly than Plasmodium falciparum irrespective of overall transmission intensity, resulting …

Glucocorticoid‐induced TNFR‐related (gitr) is a gene coding for a member of the TNF
receptor superfamily. GITR activation by its ligand (GITRL) influences the activity of effector …