Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives
In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1–12) and
(substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues …
(substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues …
The role of physicochemical and topological parameters in drug design
J Darlami, S Sharma - Frontiers in Drug Discovery, 2024 - frontiersin.org
Quantitative structure activity relationship (QSAR) is a widely used tool in rational drug
design that establishes relationships between the physicochemical and topological …
design that establishes relationships between the physicochemical and topological …
[HTML][HTML] Comparative biocompatibility and antimicrobial studies of sorbic acid derivates
Nowadays, the sorbates are the third largest group of antimicrobial preservatives in food and
pharmaceutical industries, following the parabens and benzoates whose safety is …
pharmaceutical industries, following the parabens and benzoates whose safety is …
Synthesis of quinoline acetohydrazide-hydrazone derivatives evaluated as DNA gyrase inhibitors and potent antimicrobial agents
The (E)-N′-(substituted-benzylidene)-2-(7-fluoro-2-methoxyquinolin-8-yl) acetohydrazide-
hydrazone derivatives reported in this manuscript represent a new series of antibacterial …
hydrazone derivatives reported in this manuscript represent a new series of antibacterial …
Synthesis and QSAR evaluation of 2-(substituted phenyl)-1H-benzimidazoles and [2-(substituted phenyl)-benzimidazol-1-yl]-pyridin-3-yl-methanones
A series of 2-(substituted phenyl)-1H-benzimidazole (1–10) and [2-(substituted phenyl)-
benzimidazol-1-yl]-pyridin-3-yl-methanone (11–19) derivatives were synthesized and tested …
benzimidazol-1-yl]-pyridin-3-yl-methanone (11–19) derivatives were synthesized and tested …
Solubility and solution thermodynamics of sorbic acid in eight pure organic solvents
J Fang, M Zhang, P Zhu, J Ouyang, J Gong… - The Journal of Chemical …, 2015 - Elsevier
By the gravimetric method, the solubility of sorbic acid in eight solvents including ethanol, 2-
propanol, methanol, 1-butanol, ethyl acetate, methyl tert-butyl ether, acetone and acetonitrile …
propanol, methanol, 1-butanol, ethyl acetate, methyl tert-butyl ether, acetone and acetonitrile …
Isonicotinic acid hydrazide derivatives: synthesis, antimicrobial activity, and QSAR studies
A series of isonicotinic acid hydrazide derivatives (1–19) was synthesized and tested in vitro
for antimycobacterial activity against Mycobacterium tuberculosis and antimicrobial activity …
for antimycobacterial activity against Mycobacterium tuberculosis and antimicrobial activity …
[HTML][HTML] Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted benzene …
Abstract A series of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted
benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro …
benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro …
Benzylidene/2-chlorobenzylidene hydrazides: Synthesis, antimicrobial activity, QSAR studies and antiviral evaluation
D Kumar, V Judge, R Narang, S Sangwan… - European Journal of …, 2010 - Elsevier
A series of benzylidene hydrazides (1–20) was synthesized and tested, in vitro, for
antibacterial, antifungal and antiviral activities. The microbial screening results indicated that …
antibacterial, antifungal and antiviral activities. The microbial screening results indicated that …
Synthesis, antimycobacterial, antiviral, antimicrobial activities, and QSAR studies of nicotinic acid benzylidene hydrazide derivatives
A series of nicotinic acid benzylidene hydrazide derivatives (1–18) was synthesized and
tested in vitro for biological evaluations. The antimycobacterial activity results indicated that …
tested in vitro for biological evaluations. The antimycobacterial activity results indicated that …