Recent advances in microfluidic single-cell analysis and its applications in drug development
Y Jiao, L Gao, Y Ji, W Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Cellular heterogeneity is prevalent in all cell populations. Single-cell analysis (SCA) could
unveil the heterogeneity and thus gain unique insights into complex biological processes …
unveil the heterogeneity and thus gain unique insights into complex biological processes …
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Functional precision medicine is a new, emerging area that can guide cancer treatment by
capturing information from direct perturbations of tumor-derived, living cells, such as by drug …
capturing information from direct perturbations of tumor-derived, living cells, such as by drug …
Characterization of AI-enhanced magnetophoretic transistors operating in a tri-axial magnetic field for on-chip bioparticle sorting
R Abedini-Nassab, E Adibi, S Ahmadiasl - Scientific Reports, 2024 - nature.com
We demonstrate two general classes of magnetophoretic transistors, called the “trap” and
the “repel-and-collect” transistors, capable of switching single magnetically labeled cells and …
the “repel-and-collect” transistors, capable of switching single magnetically labeled cells and …
Microfluidic Impedance Cytometry Enabled One‐Step Sample Preparation for Efficient Single‐Cell Mass Spectrometry
Single‐cell mass spectrometry (MS) is significant in biochemical analysis and holds great
potential in biomedical applications. Efficient sample preparation like sorting (ie, separating …
potential in biomedical applications. Efficient sample preparation like sorting (ie, separating …
Convenient tumor 3D spheroid arrays manufacturing via acoustic excited bubbles for in situ drug screening
J Zheng, X Hu, X Gao, Y Liu, S Zhao, L Chen, G He… - Lab on a Chip, 2023 - pubs.rsc.org
The quick and convenient fabrication of in vitro tumor spheroids models has been pursued
for clinical drug discovery and personalized therapy. Here, uniform three-dimensional (3D) …
for clinical drug discovery and personalized therapy. Here, uniform three-dimensional (3D) …
Performance-enhanced clogging-free viscous sheath constriction impedance flow cytometry
As a label-free and high-throughput single cell analysis platform, impedance flow cytometry
(IFC) suffers from clogging caused by a narrow microchannel as mechanical constriction …
(IFC) suffers from clogging caused by a narrow microchannel as mechanical constriction …
Transcribing the enigma: the B chromosome as a territory of uncharted RNAs
B chromosomes are supernumerary elements found in several groups of eukaryotes,
including fungi, plants, and animals. Typically, these chromosomes either originate from …
including fungi, plants, and animals. Typically, these chromosomes either originate from …
One-step fabrication of droplet arrays using a biomimetic structural chip
L Du, Y Li, X Zhang, Z Zhou, Y Wang… - ACS Applied Materials …, 2023 - ACS Publications
In the field of one-step efficient preparation of dewetting droplet arrays, the process is
hampered by the requirement for low chemical wettability of solid surfaces, which restricts …
hampered by the requirement for low chemical wettability of solid surfaces, which restricts …
Recent advances in microfluidics for single-cell functional proteomics
Single-cell proteomics (SCP) reveals phenotypic heterogeneity by profiling individual cells,
their biological states and functional outcomes upon signaling activation that can hardly be …
their biological states and functional outcomes upon signaling activation that can hardly be …
Enhancing microdroplet array generation via heterogeneous inner surface Modification: Biomimetic & hydrophobic approach
L Du, Z Zhou, J Wang, D Zhang, Y Li, J Zhou… - Chemical Engineering …, 2024 - Elsevier
Microdroplet array chips have great potential for biological applications. Both physical
structure and chemical material modification are effective surface modification techniques for …
structure and chemical material modification are effective surface modification techniques for …