Tissue factor pathway inhibitor-2 (TFPI-2) is a 32 kDa matrix-associated Kunitz-type serine
proteinase inhibitor consisting of a short amino-terminal region, three tandem Kunitz-type …

Tissue factor pathway inhibitor-2 (TFPI-2), a member of the Kunitz-type serine proteinase
inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). The …

Matrix metalloproteinases (MMP) including MMP-2 and MMP-9 play a major role in tumour
invasion by proteolysing the extracellular matrix. Their activation, particularly that of MMP-9 …

Clotting activation occurs frequently in cancer. Tissue factor (TF), the most potent initiator of
coagulation, is expressed aberrantly in many types of malignancy and is involved not only in …

In HCC, inactivation of tumor suppressor genes plays a significant role in carcinogenesis.
Apart from deletions and mutations, growing evidence has indicated that epigenetic …

A statistical method for combining multiple microarray studies has been previously
developed by the authors. Here, we present the application of the method to our …

Tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine proteinase inhibitor that
inhibits plasmin-dependent activation of several metalloproteinases. Downregulation of TFPI …

Of all of the epithelial ovarian cancers (EOC), clear cell adenocarcinoma (CCA) has the
worst clinical prognosis. Furthermore, the conventional EOC biomarker CA125 is more often …

The progression of neoplasms is frequently associated with thromboembolic complications.
Coagulation proteins, particularly tissue factor (TF), have been shown to play a role in tumor …

Human tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine protease inhibitor
that inhibits plasmin, trypsin, chymotrypsin, cathepsin G, and plasma kallikrein but not …