Purpose: The CYP2C19 isoenzyme plays an important role in the efficacy and safe use of
many drugs. The aim of this review is to demonstrate how CYP2C19 mutations influence …

Introduction Racial and ethnic categories are frequently used in pharmacogenetics literature
to stratify patients; however, these categories can be inconsistent across different studies. To …

Compared to Europe, data on genetic variation in genes transcribing drug metabolizing
enzymes among Asian is limited due to ethnic diversity. Here we compare frequencies for …

Background: Genetic polymorphism of CYP2C19 has been shown to affect enzyme activity
and thereby contribute to inter-individual variability in drug metabolism and response. The …

Eliminating the Plasmodium vivax malaria parasite infection remains challenging. One of the
main problems is its capacity to form hypnozoites that potentially lead to recurrent infections …

Introduction CYP2C19 plays a major role in the metabolism of various drugs. The most
common genetic variants were the CYP2C19* 2 and* 3 alleles (rs4244285 and rs4986893 …

Differences in the distribution of RBC antigens defining the blood group types among
different populations have been well established. Fewer studies exist that have explored the …

Simple Summary CYP2C19 is known as an enzyme primarily responsible for metabolizing
various drugs, such as proton pump inhibitor, antiplatelet, anti-epileptic, and anticoagulant …

Background: CYP3A5 is the predominant sub-family of biotransformation enzymes in the
liver and the genetic variations in CYP3A5 are an important determinant of inter-individual …

Tôi xin cam đoan số liệu trong đề tài luận án có một phần (nhóm chứng) số liệu trong đề tài
nghiên cứu cấp nhà nước có tên “Nghiên cứu tình trạng một số gen liên quan chuyển hóa …