[HTML][HTML] Predictive factors associated with hepatitis C antiviral therapy response
LN Cavalcante, AC Lyra - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection may lead to significant liver injury, and viral, environmental,
host, immunologic and genetic factors may contribute to the differences in the disease …
host, immunologic and genetic factors may contribute to the differences in the disease …
Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C
MA Jiménez-Sousa, A Fernández-Rodríguez… - BMC medicine, 2013 - Springer
Background Since 2009, several studies have identified single-nucleotide polymorphisms
(SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated …
(SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated …
Impact of new hepatitis C treatments in different regions of the world
L Wei, ASF Lok - Gastroenterology, 2014 - gastrojournal.org
(HCV) and the availability of interferon (IFN)-free and soon ribavirin-free treatment regimens
of 12 weeks duration with sustained virologic response (SVR) rates of> 90% has stimulated …
of 12 weeks duration with sustained virologic response (SVR) rates of> 90% has stimulated …
Host genetic variants in the pathogenesis of hepatitis C
M Rau, K Baur, A Geier - Viruses, 2012 - mdpi.com
Direct-acting antiviral drugs (DAAs) are currently replacing antiviral therapy for Hepatitis C
infection. Treatment related side effects are even worse and the emergence of resistant …
infection. Treatment related side effects are even worse and the emergence of resistant …
Pharmacogenomics research and clinical implementation in Brazil
F Rodrigues‐Soares… - Basic & Clinical …, 2019 - Wiley Online Library
We searched PubMed entries and the Lattes database of Brazilian Pharmacogenetics
Network investigators, for pharmacogenetic/genomic (PGx) studies in the Brazilian …
Network investigators, for pharmacogenetic/genomic (PGx) studies in the Brazilian …
IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients
N Echeverría, D Chiodi, P López, A Sanchez Ciceron… - Virology journal, 2018 - Springer
Background Host single-nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B)
locus are associated with sustained virological response to antiviral therapy and with …
locus are associated with sustained virological response to antiviral therapy and with …
IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers
T Assone, FV Souza, KO Gaester… - PLoS neglected …, 2014 - journals.plos.org
Background The polymorphisms of IL28B have been described as important in the
pathogenesis of infections caused by some viruses. The aim of this research was to evaluate …
pathogenesis of infections caused by some viruses. The aim of this research was to evaluate …
Meta‐analysis: the impact of IL 28 B polymorphisms on rapid and sustained virological response in HCV‐2 and‐3 patients
J Schreiber, C Moreno, BG Garcia… - Alimentary …, 2012 - Wiley Online Library
Background Recent studies suggested that IL 28 B polymorphisms may affect rapid and
sustained virological response rates in HCV patients infected with genotype 2 or 3. Aim To …
sustained virological response rates in HCV patients infected with genotype 2 or 3. Aim To …
Interferon-lambda 3 and 4 polymorphisms increase sustained virological responses and regulate innate immunity in antiviral therapy with pegylated interferon-alpha
AMV Silva, LE Alvarado-Arnez, T Azamor… - Frontiers in Cellular …, 2021 - frontiersin.org
Sustained virologic response (SVR) in chronic hepatitis C (CHC) treatment denotes that the
host genetics controls the immune response and unequivocally contribute to viral clearance …
host genetics controls the immune response and unequivocally contribute to viral clearance …
A single nucleotide polymorphism, rs129679860, in the IL28B locus is associated with the viral kinetics and a sustained virological response in a chronic …
JA Ramos, ALA Ramos, L Hoffmann… - Memórias do Instituto …, 2012 - SciELO Brasil
Single nucleotide polymorphisms (SNPs) in the interleukin (IL) 28B locus have been
associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV) …
associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV) …