Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Significance: An abundance of experimental evidence suggests that hydrogen sulfide (H2S)
plays a prominent role in physiology and pathophysiology. Many targets exist for H2S …

Significance: Diabetes and its complications represent a major socioeconomic problem.
Recent Advances: Changes in the balance of hydrogen sulfide (H2S) play an important role …

Endothelial dysfunction (EDF) reflects pathophysiological changes in the phenotype and
functions of endothelial cells that result from and/or contribute to a plethora of cardiovascular …

Hydrogen sulfide (H2S) therapy protects nondiabetic animals in various models of
myocardial injury, including acute myocardial infarction and heart failure. Here, we sought to …

Diabetes is one of the most prevalent metabolic disorders and is estimated to affect 400
million of 4.4% of population worldwide in the next 20 year. In diabetes, risk to develop …

Recently, myriad studies have defined the versatile abilities of gasotransmitters and their
synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non …

Significance: Diabetes and its related complications are becoming an increasing public
health problem that affects hundreds of millions of people globally. Increased disability and …

Background: Bone marrow cell (BMC)–based treatment for critical limb ischemia in diabetic
patients yielded a modest therapeutic effect resulting from cell dysfunction. Therefore …

In the past decades three gaseous signaling molecules—so-called gasotransmitters—have
been identified: nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) …