Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury

W Li, Z Xiang, Y Xing, S Li, S Shi - Cell death & disease, 2022 - nature.com
Ferroptosis, a form of regulated cell death, plays an important role in acute kidney injury
(AKI). Previous studies have shown that prolyl hydroxylase domain protein (PHD) inhibitors …

A review of ApoE4 interference targeting Mitophagy molecular pathways for Alzheimer's disease

H Chen, F Chen, Y Jiang, L Zhang, G Hu… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is one of the major worldwide causes of dementia that is
characterized by irreversible decline in learning, memory loss, and behavioral impairments …

The role of DRP1-PINK1-Parkin-mediated mitophagy in early cadmium-induced liver damage

J Sun, F Yu, T Wang, J Bian, Z Liu, H Zou - Toxicology, 2022 - Elsevier
Cadmium (Cd) is an important environmental pollutant that causes varying degrees of
damage to multiple systems of the body. However, the specific mechanism of Cd-induced …

Beyond the classical amyloid hypothesis in Alzheimer's disease: Molecular insights into current concepts of pathogenesis, therapeutic targets, and study models

A Theerasri, S Janpaijit, T Tencomnao… - WIREs Mechanisms …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the progressive neurodegenerative disorders and the
most common cause of dementia in the elderly worldwide causing difficulties in the daily life …

[HTML][HTML] Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation

H Weng, Q Wang, R Ye, Y Bai, H Yang, G Xu… - Integrative Medicine …, 2023 - Elsevier
Background Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative
disease. Oxidative stress emerges at the early AD stage. As a non-invasive therapy with few …

Unraveling mitochondrial dysfunction: comprehensive perspectives on its impact on neurodegenerative diseases

AA Mohamed Yusoff, SZN Mohd Khair - Reviews in the …, 2024 - degruyter.com
Neurodegenerative diseases represent a significant challenge to modern medicine, with
their complex etiology and progressive nature posing hurdles to effective treatment …