Measuring the tail: Methods for poly (A) tail profiling
A Brouze, PS Krawczyk… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Abstract The 3′‐end poly (A) tail is an important and potent feature of most mRNA
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing
CJ Herrmann, R Schmidt, A Kanitz, P Artimo… - Nucleic acids …, 2020 - academic.oup.com
Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly
(A)) sites, alternative terminal exons account for much of the variation between human …
(A)) sites, alternative terminal exons account for much of the variation between human …
Mechanisms of lineage specification in Caenorhabditis elegans
The studies of cell fate and lineage specification are fundamental to our understanding of
the development of multicellular organisms. Caenorhabditis elegans has been one of the …
the development of multicellular organisms. Caenorhabditis elegans has been one of the …
Specialized germline P-bodies are required to specify germ cell fate in Caenorhabditis elegans embryos
M Cassani, G Seydoux - Development, 2022 - journals.biologists.com
In animals with germ plasm, specification of the germline involves 'germ granules',
cytoplasmic condensates that enrich maternal transcripts in the germline founder cells. In …
cytoplasmic condensates that enrich maternal transcripts in the germline founder cells. In …
mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage
DM Parker, LP Winkenbach, S Boyson… - …, 2020 - journals.biologists.com
Caenorhabditis elegans early embryos generate cell-specific transcriptomes despite lacking
active transcription, thereby presenting an opportunity to study mechanisms of post …
active transcription, thereby presenting an opportunity to study mechanisms of post …
The role of RNA-binding proteins in orchestrating germline development in Caenorhabditis elegans
MMY Albarqi, SP Ryder - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
RNA passed from parents to progeny controls several aspects of early development. The
germline of the free-living nematode Caenorhabditis elegans contains many families of …
germline of the free-living nematode Caenorhabditis elegans contains many families of …
Germline immortality relies on TRIM32-mediated turnover of a maternal mRNA activator in C. elegans
TD Oyewale, CR Eckmann - Science Advances, 2022 - science.org
How the germ line achieves a clean transition from maternal to zygotic gene expression
control is a fundamental problem in sexually reproducing organisms. Whereas several …
control is a fundamental problem in sexually reproducing organisms. Whereas several …
CYP Gene Expression and In Vivo Biological Effects of Khat Ethanol Extract, Cathinone and Cathine in Caenorhabditis elegans
SYM Lim, MA Alshawsh… - … In Microbes & …, 2023 - journals.hh-publisher.com
The significant influence of khat, cathinone, and cathine on appetite suppression,
reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely …
reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely …
The endogenous mex-3 3´UTR is required for germline repression and contributes to optimal fecundity in C. elegans
MMY Albarqi, SP Ryder - PLoS Genetics, 2021 - journals.plos.org
RNA regulation is essential to successful reproduction. Messenger RNAs delivered from
parent to progeny govern early embryonic development. RNA-binding proteins (RBPs) are …
parent to progeny govern early embryonic development. RNA-binding proteins (RBPs) are …
C22 disrupts embryogenesis and extends C. elegans lifespan
S Beydoun, A Sridhar, AM Tuckowski, E Wang… - Frontiers in …, 2023 - frontiersin.org
Caenorhabditis elegans is an instrumental model in aging research due to its large brood
size, short lifespan, and malleable genetics. However, maintaining a synchronous nematode …
size, short lifespan, and malleable genetics. However, maintaining a synchronous nematode …