Mathematical modeling has become a valuable tool in the continued effort to understand,
predict, and ultimately treat a wide range of cancers in recent years. 1, 2 By describing …

Numerous aspects of the immune system operate on the basis of complex regulatory
networks that are amenable to mathematical and computational modeling. Several modeling …

In this paper, a detailed mathematical study of cancer immunotherapy will be presented.
General principles of cancer immunotherapy and the model equations and hypotheses will …

Immunotherapy has shown great potential in the treatment of cancer; however, only a
fraction of patients respond to treatment, and many experience autoimmune‐related side …

In this paper, a tumor and Lymphatic immune system interaction model with two time delays
is discussed in which the delays describe the proliferation of tumor cells and the …

A next generation approach to cancer envisions developing preventative vaccinations to
stimulate a person's immune cells, particularly cytotoxic T lymphocytes (CTLs), to eliminate …

A coupled ordinary differential equation model of tumour-immune dynamics is presented
and analysed. The model accounts for biological and clinical factors which regulate the …

Immunological studies frequently analyze individual components (eg, signaling pathways) of
immune systems in a reductionist manner. In contrast, systems immunology aims to give a …

The interactions between a solid tumor and the immune system are described both prior to
and after neovascularization by a predator-prey model, and predictions about tumor …

The activity of natural killer (NK) cells is regulated by various processes including
education/licensing, priming, integration of positive and negative signals through an array of …