Covering: up to 2013 Although holo-acyl carrier protein synthase, AcpS, a
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …

▪ Abstract The type II fatty acid synthetic pathway is the principal route for the production of
membrane phospholipid acyl chains in bacteria and plants. The reaction sequence is …

The type II fatty acid synthase consists of a series of individual enzymes, each encoded by a
separate gene, that catalyze discrete steps in chain elongation. The formation of fatty acids …

Antibiotic resistance is a serious public health concern, and new drugs are needed to
ensure effective treatment of many bacterial infections. Bacterial type II fatty acid synthesis …

Apicomplexan parasitic diseases impose devastating impacts on much of the world's
population. The increasing prevalence of drug resistant parasites and the growing number …

PPTases (phosphopantetheinyl transferases) are of great interest owing to their essential
roles in activating fatty acid, polyketide and non-ribosomal peptide synthetase enzymes for …

4′-Phosphopantetheinyl transferases (PPTases) catalyze a post-translational modification
essential to bacterial cell viability and virulence. We present the discovery and medicinal …

Allylic azlactones are greatly significant in terms of potential bioactivities and synthetic
applications. Owing to the burgeoning interest of the pharmaceutical industry in α-amino …

Mild steel is used as a structural material for pipes, tank, reaction vessels, etc. which are
known to corrode invariably in contact with various solvents. From the view point of a …

Surfactin-type phosphopantetheinyl transferases (Sfp-PPTases) are responsible for
modifying type I polyketide and non-ribosomal peptide synthases of prokaryotes and have …