The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …

Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

The aim of the present study is to identify microRNAs (miRs) with high potential to be used
as biomarkers in plasma and/or serum to clinically diagnose, or provide accurate prognosis …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Rationale: MicroRNAs are small RNAs that control gene expression. Besides their cell
intrinsic function, recent studies reported that microRNAs are released by cultured cells and …

Background—Small RNA molecules, called microRNAs, freely circulate in human plasma
and correlate with varying pathologies. In this study, we explored their diagnostic potential in …

Background—Recently, elevation of circulating muscle-specific microRNA (miRNA) levels
has been reported in patients with acute myocardial infarction. However, it is still unclear …

Originally identified as moderate biological modifiers, microRNAs have recently emerged as
powerful regulators of diverse cellular processes with especially important roles in disease …

In the natural habitat of our ancestors, physical activity was not a preventive intervention but
a matter of survival. In this hostile environment with scarce food and ubiquitous dangers …