Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm.

J Eliza, P Daisy, S Ignacimuthu - Chemico-Biological Interactions, 2010 - Elsevier
Antioxidant properties of many medicinal plants have been widely recognized and some of
them have been commercially exploited. Plant derived antioxidants play a very important …

In vivo and in vitro cardioprotective effect of gossypin against isoproterenol-induced myocardial infarction injury

I Cinar, M Yayla, T Tavaci, E Toktay, RA Ugan… - Cardiovascular …, 2022 - Springer
The aim of the study was to examine the protective effects and possible mechanism of
gossypin against isoproterenol (ISO)-mediated myocardial damage in vivo and H9c2 cell …

Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways

F Imam, NO Al-Harbi, MM Al-Harbi, MA Ansari… - Pharmacological …, 2018 - Springer
Background Doxorubicin is an effective, potent and commonly used anthracycline-related
anticancer drug; however, cardiotoxicity compromises its therapeutic potential. Apremilast, a …

Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats

S Celik, S Erdogan - Molecular and cellular biochemistry, 2008 - Springer
Diabetic patients reveal significant disorders, such as nephropathy, cardiomyopathy, and
neuropathy. As oxidative stress and inflammation seem to be implicated in the pathogenesis …

Rutin attenuates carfilzomib-induced cardiotoxicity through inhibition of NF-κB, hypertrophic gene expression and oxidative stress

F Imam, NO Al-Harbi, MM Al-Harbia… - Cardiovascular …, 2017 - Springer
Carfilzomib is a proteasome inhibitor, commonly used in multiple myeloma, but its clinical
use may be limited due to cardiotoxicity. This study was aimed to evaluate the influence of …

Carotid artery atherosclerosis: what is the evidence for drug action?

SS Daskalopoulou, ME Daskalopoulos… - Current …, 2007 - ingentaconnect.com
Carotid artery disease is a well-established cause of cerebrovascular events. This risk is
predicted by the severity of stenosis and other plaque characteristics that can be …

Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats

F Imam, NO Al-Harbi, MM Al-Harbi… - Toxicology …, 2016 - Taylor & Francis
Carfilzomib (CFZ), is a potent, selective second generation proteasome inhibitor, used for
the treatment of multiple myeloma. The aim of the present study was to investigate the …

Antidiabetic effect of S-allylcysteine: effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats

G Saravanan, P Ponmurugan - Journal of Diabetes and its Complications, 2012 - Elsevier
OBJECTIVE: It is considered that diabetes mellitus and thyroid disease are the two common
endocrine disorders and also suggested that insulin and thyroid hormones influence each …

Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats

NO Al-Harbi, F Imam, MM Al-Harbi… - Journal of the renin …, 2015 - journals.sagepub.com
Introduction: Tacrolimus is frequently used as immunosuppressive agent in organ
transplantation but its clinical use is limited due to its marked nephrotoxicity. Materials and …

Riboflavin attenuates lipopolysaccharide-induced lung injury in rats

NO Al-Harbi, F Imam, A Nadeem… - Toxicology …, 2015 - Taylor & Francis
Riboflavin (vitamin B2) is an easily absorbed micronutrient with a key role in maintaining
health in humans and animals. It is the central component of the cofactors flavin adenine …