Inducible nitric oxide synthase: Regulation, structure, and inhibition
MA Cinelli, HT Do, GP Miley… - Medicinal research …, 2020 - Wiley Online Library
A considerable number of human diseases have an inflammatory component, and a key
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …
[HTML][HTML] Mechanistic insights and perspectives involved in neuroprotective action of quercetin
Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …
A perspective on Nrf2 signaling pathway for neuroinflammation: a potential therapeutic target in Alzheimer's and Parkinson's diseases
Neuroinflammation plays a pivotal role in Alzheimer's disease (AD) and Parkinson's disease
(PD), the leading causes of dementia. These neurological disorders are characterized by the …
(PD), the leading causes of dementia. These neurological disorders are characterized by the …
Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …
Oxidative stress and neurodegenerative disorders
J Li, WO, W Li, ZG Jiang, HA Ghanbari - International journal of molecular …, 2013 - mdpi.com
Living cells continually generate reactive oxygen species (ROS) through the respiratory
chain during energetic metabolism. ROS at low or moderate concentration can play …
chain during energetic metabolism. ROS at low or moderate concentration can play …
Modulation of chronic inflammation by quercetin: The beneficial effects on obesity
S Sato, Y Mukai - Journal of inflammation research, 2020 - Taylor & Francis
Obesity has become a major risk factor for the development of chronic diseases such as
insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. Moreover, obesity …
insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. Moreover, obesity …
Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons
L Guo, Z Huang, L Huang, J Liang, P Wang… - Journal of …, 2021 - Springer
Background The incidence of ischemic stroke in the context of vascular disease is high, and
the expression of growth-associated protein-43 (GAP43) increases when neurons are …
the expression of growth-associated protein-43 (GAP43) increases when neurons are …
Polyphenols: multipotent therapeutic agents in neurodegenerative diseases
KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …
Quercetin lipid nanoparticles functionalized with transferrin for Alzheimer's disease
RGR Pinheiro, A Granja, JA Loureiro… - European Journal of …, 2020 - Elsevier
Quercetin was encapsulated in lipid nanoparticles (SLN and NLC) to take advantage of its
neuroprotective properties in Alzheimer's disease. The nanoparticles were functionalized …
neuroprotective properties in Alzheimer's disease. The nanoparticles were functionalized …
Effects of food-derived bioactive peptides on cognitive deficits and memory decline in neurodegenerative diseases: A review
S Wang, D Sun-Waterhouse, GIN Waterhouse… - Trends in Food Science …, 2021 - Elsevier
Background Memory and cognitive impairments/disorders are the main clinical symptoms of
neurodegenerative diseases. The prevalence of such chronic conditions has increased over …
neurodegenerative diseases. The prevalence of such chronic conditions has increased over …