The transcription factor NRF2 (nuclear factor erythroid 2‐related factor 2) triggers the first
line of homeostatic responses against a plethora of environmental or endogenous …

Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …

The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

Protein kinases (PKs) have been recognized as central nervous system (CNS)-disease-
relevant targets due to their master regulatory role in different signal transduction cascades …

Neurodegenerative disorders are spreading worldwide and are one of the greatest threats to
public health. There is currently no adequate therapy for these disorders, and therefore there …

Several findings propose the altered tau protein network as an important target for
Alzheimer's disease (AD). Particularly, two points of pharmacological intervention can be …

Abstract Glycogen Synthase Kinase-3 (GSK-3) is a serine/threonine kinase which is
ubiquitously expressed and is regarded as a regulator for various cellular events and …

Abstract Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase is an archetypal
multifunctional moonlighting protein involved in diverse cellular processes including …

The introduction of therapeutics targeting specific tumor-promoting oncogenic or non-
oncogenic signaling pathways has revolutionized cancer treatment. Mechanistic (previously …

Glycogen synthase kinase (GSK) 3β is a multifunctional serine/threonine protein kinase with
more than 100 substrates and interacting molecules. GSK3β is normally active in cells and …