[HTML][HTML] Therapeutic glycoprotein production in mammalian cells
ME Lalonde, Y Durocher - Journal of biotechnology, 2017 - Elsevier
Over the last years, the biopharmaceutical industry has significantly turned its biologics
production towards mammalian cell expression systems. The presence of glycosylation …
production towards mammalian cell expression systems. The presence of glycosylation …
The emerging CHO systems biology era: harnessing the 'omics revolution for biotechnology
HF Kildegaard, D Baycin-Hizal, NE Lewis… - Current opinion in …, 2013 - Elsevier
Chinese hamster ovary (CHO) cells are the primary factories for biopharmaceuticals
because of their capacity to correctly fold and post-translationally modify recombinant …
because of their capacity to correctly fold and post-translationally modify recombinant …
De novo assembly and characterization of root transcriptome using Illumina paired-end sequencing and development of cSSR markers in sweetpotato (Ipomoea …
Z Wang, B Fang, J Chen, X Zhang, Z Luo, L Huang… - BMC genomics, 2010 - Springer
Background The tuberous root of sweetpotato is an important agricultural and biological
organ. There are not sufficient transcriptomic and genomic data in public databases for …
organ. There are not sufficient transcriptomic and genomic data in public databases for …
De novo assembly and characterization of bark transcriptome using Illumina sequencing and development of EST-SSR markers in rubber tree (Hevea brasiliensis …
D Li, Z Deng, B Qin, X Liu, Z Men - BMC genomics, 2012 - Springer
Background In rubber tree, bark is one of important agricultural and biological organs.
However, the molecular mechanism involved in the bark formation and development in …
However, the molecular mechanism involved in the bark formation and development in …
Comprehensive analysis of the Corynebacterium glutamicum transcriptome using an improved RNAseq technique
Abstract Background The use of RNAseq to resolve the transcriptional organization of an
organism was established in recent years and also showed the complexity and dynamics of …
organism was established in recent years and also showed the complexity and dynamics of …
Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp. strain PCC 7120 to combined-nitrogen deprivation
BL Flaherty, F Van Nieuwerburgh, SR Head… - BMC genomics, 2011 - Springer
Background Cyanobacteria are potential sources of renewable chemicals and biofuels and
serve as model organisms for bacterial photosynthesis, nitrogen fixation, and responses to …
serve as model organisms for bacterial photosynthesis, nitrogen fixation, and responses to …
Genomic sequencing and analysis of a Chinese hamster ovary cell line using Illumina sequencing technology
S Hammond, JC Swanberg, M Kaplarevic, KH Lee - BMC genomics, 2011 - Springer
Background Chinese hamster ovary (CHO) cells are among the most widely used hosts for
therapeutic protein production. Yet few genomic resources are available to aid in …
therapeutic protein production. Yet few genomic resources are available to aid in …
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing
The pyrosequencing technology from 454 Life Sciences and a novel assembly approach for
cDNA sequences with the Newbler Assembler were used to achieve a major step forward to …
cDNA sequences with the Newbler Assembler were used to achieve a major step forward to …
Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines
Chinese hamster ovary (CHO) cell lines represent the most commonly used mammalian
expression system for the production of therapeutic proteins. In this context, detailed …
expression system for the production of therapeutic proteins. In this context, detailed …
[HTML][HTML] Advances in improving mammalian cells metabolism for recombinant protein production
C Altamirano, J Berrios, M Vergara… - Electronic Journal of …, 2013 - SciELO Chile
Background: The production of recombinant proteins for therapeutic use represents a great
impact on the biotechnology industry. In this context, established mammalian cell lines …
impact on the biotechnology industry. In this context, established mammalian cell lines …