Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight
Diabetes mellitus is the prominent metabolic disorder affecting 422 million people around
the globe and cause severe associated problems like kidney disorders, heart and nervous …
the globe and cause severe associated problems like kidney disorders, heart and nervous …
Elucidation of collagen amino acid interactions with metals (B, Ni) encapsulated graphene/PEDOT material: insight from DFT calculations and MD simulation
RA Timothy, H Louis, EA Adindu, TE Gber… - Journal of Molecular …, 2023 - Elsevier
Collagen amino acids play a pivotal role as essential building blocks within diverse
biological structures. Exploring their interactions with composite materials holds the potential …
biological structures. Exploring their interactions with composite materials holds the potential …
In vitro α-glucosidase and α-amylase inhibitory potential and molecular docking studies of benzohydrazide based imines and thiazolidine-4-one derivatives
Benzohydrazide based imine derivatives (1c-16c) and thiazolidine-4-one derivatives (1d-
16d) were synthesized and characterized with different spectroscopic techniques ie HREI …
16d) were synthesized and characterized with different spectroscopic techniques ie HREI …
DFT, molecular docking, molecular dynamics simulation, MMGBSA calculation and hirshfeld surface analysis of 5-sulfosalicylic acid
A Fatima, H Arora, P Bhattacharya, N Siddiqui… - Journal of Molecular …, 2023 - Elsevier
Experimental studies were conducted on 5-Sulfosalicylic Acid (5-SSA) using NMR (1Hsingle
bondNMR and 13 Csingle bondNMR), FT-IR, UV–Visible, and quantum chemical methods …
bondNMR and 13 Csingle bondNMR), FT-IR, UV–Visible, and quantum chemical methods …
Docking study, molecular dynamic, synthesis, anti-α-glucosidase assessment, and ADMET prediction of new benzimidazole-Schiff base derivatives
The control of postprandial hyperglycemia is an important target in the treatment of type 2
diabetes mellitus (T2DM). As a result, targeting α-glucosidase as the most important enzyme …
diabetes mellitus (T2DM). As a result, targeting α-glucosidase as the most important enzyme …
Synthesis, crystal structure, hirshfeld surface analysis, DFT calculations, anti-diabetic activity and molecular docking studies of (E)-N'-(5-bromo-2-hydroxybenzylidene) …
K Karrouchi, S Fettach, MM Jotani, A Sagaama… - Journal of Molecular …, 2020 - Elsevier
In this present work, the newly synthesized compound E)-N'-(5-bromo-2-
hydroxybenzylidene) isonicotinohydrazide (2) has been synthesized and characterized by …
hydroxybenzylidene) isonicotinohydrazide (2) has been synthesized and characterized by …
Synthesis of the first mixed ligand Mn (II) and Cd (II) complexes of 4‐methoxy‐pyridine‐2‐carboxylic acid, molecular docking studies and investigation of their anti …
Ö Tamer, H Mahmoody, KF Feyzioğlu… - Applied …, 2020 - Wiley Online Library
The first mixed ligand Mn (II) and Cd (II) complexes containing 4‐methoxy‐pyridine‐2‐
carboxylic acid (4‐mpic) and 4, 4′‐dimethyl‐2, 2′‐bipyridine (dmbpy) were synthesized in …
carboxylic acid (4‐mpic) and 4, 4′‐dimethyl‐2, 2′‐bipyridine (dmbpy) were synthesized in …
Nonlinear optical properties of pyrene-based chalcone:(E)-1-(4′-bromo-[1, 1′-biphenyl]-4-yl)-3-(pyren-1-yl) prop-2-en-1-one, a structure-activity study
The presence of CH… O and π… π stacking, which form a head to tail and face to face
arrangement chain along the b-axis, was shown by single crystal analysis. The small …
arrangement chain along the b-axis, was shown by single crystal analysis. The small …
A novel series of mixed-ligand M (II) complexes containing 2, 2′-bipyridyl as potent α-glucosidase inhibitor: synthesis, crystal structure, DFT calculations, and …
Diabetes mellitus (DM) is a common degenerative disease and characterized by high blood
glucose levels. Since the effective antidiabetic treatments attempt to decrease blood glucose …
glucose levels. Since the effective antidiabetic treatments attempt to decrease blood glucose …
Synthesis, molecular docking study of thiazole derivatives and exploring their dual inhibitor potentials against α-amylase and α-glucosidase
Diabetes mellitus is one of the most chronic metabolic diseases. The current study
comprises of evaluation of thiazole as an antidiabetic agent. A library of sixteen derivatives …
comprises of evaluation of thiazole as an antidiabetic agent. A library of sixteen derivatives …