Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …

The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now
widely recognized for their multifunctional roles in both the innate and adaptive immune …

Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions.
These effector molecules of the innate immune system of many vertebrates are diverse in …

Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …