The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …

Chimeric antigen receptor (CAR)-T cell therapy has achieved successful outcomes against
hematological malignancies and provided a new impetus for treating solid tumors. However …

Chemokines mediate numerous physiological and pathological processes related primarily
to cell homing and migration. The chemokine CXCL12, also known as stromal cell-derived …

Chemokines, small pro-inflammatory chemoattractant cytokines that bind to specific G-
protein-coupled seven-span transmembrane receptors, are major regulators of cell …

A complex network of chemokines and their receptors influences the development of primary
tumours and metastases. New information about the biological role of chemokines in these …

Chemokines play a vital role in tumor progression and metastasis. Chemokines are involved
in the growth of many cancers including breast cancer, ovarian cancer, pancreatic cancer …

The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12
[CXCL12]) regulates many essential biological processes, including cardiac and neuronal …

Signals from the microenvironment have a profound influence on the maintenance and/or
progression of hematopoietic and epithelial cancers. Mesenchymal or marrow-derived …

Malignant cells from at least 23 different types of cancer express the chemokine receptor
CXCR4 and respond to its ligand CXCL12. This receptor ligand pair appears to be involved …

Chemokines, small pro-inflammatory chemoattractant cytokines, that bind to specific G-
protein-coupled seven-span transmembrane receptors present on plasma membranes of …