Design, synthesis and anticancer evaluation of novel tetrahydroquinoline derivatives containing sulfonamide moiety

MM Ghorab, FA Ragab, MM Hamed - European journal of medicinal …, 2009 - Elsevier
Sulfonamides posses many types of biological activities and have recently been reported to
show substantial antitumor activity in vitro and/or in vivo. There are a variety of mechanisms …

Design, synthesis and molecular modeling of pyrazole–quinoline–pyridine hybrids as a new class of antimicrobial and anticancer agents

CB Sangani, JA Makawana, X Zhang… - European Journal of …, 2014 - Elsevier
A new series of pyrazole–quinoline–pyridine hybrids were designed based on molecular
hybridization technique and synthesized by a base-catalyzed cyclocondensation reaction …

In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido [4, 5-b] quinolines bearing a sulfonamide moiety

MM Ghorab, FA Ragab, HI Heiba, RK Arafa… - European journal of …, 2010 - Elsevier
Sulfonamide bearing compounds posses many types of biological activities and have
recently been reported to show substantial antitumor activity in vitro and/or in vivo. There are …

New arylated benzo[h]quinolines induce anti-cancer activity by oxidative stress-mediated DNA damage

DK Yadav, R Rai, N Kumar, S Singh, S Misra… - Scientific reports, 2016 - nature.com
The anti-cancer activity of the benzo [h] quinolines was evaluated on cultured human skin
cancer (G361), lung cancer (H460), breast cancer (MCF7) and colon cancer (HCT116) cell …

[HTML][HTML] Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma

T Prashanth, BRV Avin, P Thirusangu… - Biomedicine & …, 2019 - Elsevier
The synthesis and antiproliferative effect of a series of quinoline and thiazole containing
coumarin analogs 12a-d and 13a-f respectively, on mice leukemic cells was performed. The …

Synthesis and in vitro anticancer evaluation of some novel hexahydroquinoline derivatives having a benzenesulfonamide moiety

MS Al-Said, MM Ghorab, MS Al-Dosari… - European journal of …, 2011 - Elsevier
Inhibition of carbonic anhydrase isozymes has been found to have a role in the treatment of
cancer. Several sulfonamide compounds bearing an aromatic or a heteroaromatic ring were …

Antitumor activity of Dendrophthoe falcata against ehrlich ascites carcinoma in swiss albino mice

N Dashora, V Sodde, J Bhagat, KS Prabhu… - Pharmaceutical …, 2011 - benthamopen.com
The objective of the present study is to explore the anticancer activity of the ethanolic and
aqueous extracts of the Dendrophthoe falcata in Swiss albino mice against Ehrlich Ascites …

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of Premna herbacea Roxb. in Ehrlich ascites carcinoma model and Dalton's lymphoma …

I Dhamija, N Kumar, SN Manjula, V Parihar… - Experimental and …, 2013 - Elsevier
In the present study, the root nodules of Premna herbacea Roxb.(PH) was investigated for its
in vitro cytotoxicity and in vivo antitumor activity. Two extracts, aqueous and alcoholic; two …

Synthesis and biological evaluation of 2-amino-7, 7-dimethyl 4-substituted-5-oxo-1-(3, 4, 5-trimethoxy)-1, 4, 5, 6, 7, 8-hexahydro-quinoline-3-carbonitrile derivatives as …

SI Alqasoumi, AM Al-Taweel, AM Alafeefy… - Bioorganic & medicinal …, 2009 - Elsevier
A large number of antimitotic drugs, derived from natural sources or chemically synthesized,
have been identified and shown to interfere with the tubulin system. Inhibition of tubulin …

[PDF][PDF] Fused Qulnolines. Recent Synthetic Approaches to Azoloquinollnes. A Review

M Abass - Heterocycles-Sendai Institute of Heterocyclic …, 2005 - triggered.edina.clockss.org
Azoloquinoline derivatives such as pyrrolo-, furo-, thienoquinolines and their benzo or
heterocyclic annelated derivatives have attracted interest for their important biological …