TGF-β signaling in health, disease, and therapeutics

Z Deng, T Fan, C Xiao, H Tian, Y Zheng, C Li… - Signal transduction and …, 2024 - nature.com
Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every
tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular …

Psychedelics and anti-inflammatory activity in animal models

TW Flanagan, CD Nichols - Disruptive Psychopharmacology, 2022 - Springer
Abstract The serotonin (5-hydroxytryptamine, 5-HT) 2A receptor is most well known as the
common target for classic psychedelic compounds. Interestingly, the 5-HT2A receptor is the …

5-HT2 receptor activation alleviates airway inflammation and structural remodeling in a chronic mouse asthma model

TW Flanagan, MN Sebastian, DM Battaglia, TP Foster… - Life sciences, 2019 - Elsevier
Aims Although the bulk of research into the biology of serotonin 5-HT 2A receptors has
focused on its role in the CNS, selective activation of these receptors in peripheral tissues …

Virus-like particles as carrier systems to enhance immunomodulation in allergen immunotherapy

M Anzaghe, S Schülke, S Scheurer - Current allergy and asthma reports, 2018 - Springer
Abstract Purpose of Review Utilization of virus-like particles (VLPs) is considered to improve
allergen-specific immunotherapy (AIT). AIT aims at the efficient uptake of the target allergen …

Effects of the combined extracts of Herba Epimedii and Fructus Ligustrilucidi on airway remodeling in the asthmatic rats with the treatment of budesonide

X Tang, H Nian, X Li, Y Yang, X Wang, L Xu… - … and alternative medicine, 2017 - Springer
Background Asthma is characterized by chronic airway inflammation, leading to structura1
changes in the airway, collectively termed airway remodeling. Airway remodeling is thought …

Novel adjuvants in allergen-specific immunotherapy: where do we stand?

YJ Lin, J Zimmermann, S Schülke - Frontiers in Immunology, 2024 - frontiersin.org
Type I hypersensitivity, or so-called type I allergy, is caused by Th2-mediated immune
responses directed against otherwise harmless environmental antigens. Currently, allergen …

All the small things: How virus‐like particles and liposomes modulate allergic immune responses

B Kratzer, S Hofer, M Zabel… - European Journal of …, 2020 - Wiley Online Library
Recent years have seen a dramatic increase in the range of applications of virus‐like
nanoparticle (VNP)‐and liposome‐based antigen delivery systems for the treatment of …

Combined extracts of Epimedii folium and Ligustri Lucidi Fructus with budesonide attenuate airway remodeling in the asthmatic rats by regulating apoptosis and …

Z Ma, X Tang, Y Gao, H Wang, P Yu… - … and Alternative Medicine, 2020 - Wiley Online Library
This study aimed to investigate the effects of the coadministration of budesonide (Bud) and
the extracts of Epimedii Folium and Ligustri Lucidi Fructus (EEL) on regulating apoptosis …

Maternal obesity in mice exacerbates the allergic inflammatory response in the airways of male offspring

RR e-Lacerda, CJ Teixeira, S Bordin, E Antunes… - Nutrients, 2019 - mdpi.com
It was previously demonstrated that non-allergen-sensitized rodents born to mothers
exposed to a high-fat diet (HFD) spontaneously develop lower respiratory compliance and …

[HTML][HTML] 喘息婴幼儿外周血气道炎症相关介质水平的研究

余小河, 何苗, 郑湘榕, 王霞, 旷健 - Chinese Journal of …, 2019 - ncbi.nlm.nih.gov
喘息婴幼儿外周血气道炎症相关介质水平的研究- PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …