Primary cilia as dynamic and diverse signalling hubs in development and disease
Primary cilia, antenna-like sensory organelles protruding from the surface of most vertebrate
cell types, are essential for regulating signalling pathways during development and adult …
cell types, are essential for regulating signalling pathways during development and adult …
Stimuli-responsive polymer-based nanosystems for cancer theranostics
D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …
Ångström-resolution fluorescence microscopy
SCM Reinhardt, LA Masullo, I Baudrexel, PR Steen… - Nature, 2023 - nature.com
Fluorescence microscopy, with its molecular specificity, is one of the major characterization
methods used in the life sciences to understand complex biological systems. Super …
methods used in the life sciences to understand complex biological systems. Super …
Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit
A fundamental challenge in fluorescence microscopy is the photon shot noise arising from
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …
Super-resolution microscopy for structural cell biology
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
Endosomal escape: A bottleneck for LNP-mediated therapeutics
S Chatterjee, E Kon, P Sharma… - Proceedings of the …, 2024 - National Acad Sciences
Lipid nanoparticles (LNPs) have recently emerged as a powerful and versatile clinically
approved platform for nucleic acid delivery, specifically for mRNA vaccines. A major …
approved platform for nucleic acid delivery, specifically for mRNA vaccines. A major …
The new era of high-throughput nanoelectrochemistry
To acquire a deeper understanding of electrochemical systems requires techniques that
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …
Small-molecule fluorogenic probes for mitochondrial nanoscale imaging
R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …
Small size, big impact: recent progress in bottom‐up synthesized nanographenes for optoelectronic and energy applications
Bottom‐up synthesized graphene nanostructures, including 0D graphene quantum dots and
1D graphene nanoribbons, have recently emerged as promising candidates for efficient …
1D graphene nanoribbons, have recently emerged as promising candidates for efficient …
Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus
Proteins critical for synaptic transmission are non-uniformly distributed and assembled into
regions of high density called subsynaptic densities (SSDs) that transsynaptically align in …
regions of high density called subsynaptic densities (SSDs) that transsynaptically align in …