Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine

CY Wu, CW Cheng, CC Kung… - Proceedings of the …, 2022 - National Acad Sciences
Development of the messenger RNA (mRNA) vaccine has emerged as an effective and
speedy strategy to control the spread of new pathogens. After vaccination, the mRNA is …

Distinct core glycan and O-glycoform utilization of SARS-CoV-2 Omicron variant Spike protein RBD revealed by top-down mass spectrometry

DS Roberts, M Mann, BH Li, D Kim, AR Braiser… - Chemical …, 2022 - pubs.rsc.org
The SARS-CoV-2 Omicron (B. 1.1. 529) variant possesses numerous spike (S) mutations
particularly in the S receptor-binding domain (S-RBD) that significantly improve …

[HTML][HTML] Glycosylation and serological reactivity of an expression-enhanced SARS-CoV-2 viral spike mimetic

H Chawla, SE Jossi, SE Faustini, F Samsudin… - Journal of Molecular …, 2022 - Elsevier
Extensive glycosylation of viral glycoproteins is a key feature of the antigenic surface of
viruses and yet glycan processing can also be influenced by the manner of their …