New insights and potential therapeutic interventions in metabolic diseases

VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …

Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?

CM Fuhri Snethlage, D de Wit… - Immunological …, 2024 - Wiley Online Library
Summary Type 1 diabetes (T1D) is a chronic autoimmune disease targeting insulin‐
producing pancreatic beta cells. T1D is a multifactorial disease incorporating genetic and …

Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: challenges and opportunities

S Zhidu, T Ying, J Rui, Z Chao - Stem Cell Research & Therapy, 2024 - Springer
Advances in stem cell technology offer new possibilities for patients with untreated diseases
and disorders. Stem cell-based therapy, which includes multipotent mesenchymal stem cells …

The promise of CRISPR/Cas9 technology in diabetes mellitus therapy: How gene editing is revolutionizing diabetes research and treatment

Y Cheng, H Wang, M Li - Journal of Diabetes and its Complications, 2023 - Elsevier
Diabetes mellitus is a metabolic disease, characterized by chronic hyperglycemia caused by
an abnormality in insulin secretion or action. Millions of people across the world are affected …

LPS-pretreatment adipose-derived mesenchymal stromal cells promote wound healing in diabetic rats by improving angiogenesis

K Wang, Z Chen, L Jin, L Zhao, L Meng, F Kong, C He… - Injury, 2022 - Elsevier
Mesenchymal stem cells (MSCs) play a key role in wound healing, and the advantages of
pretreated MSCs in wound healing have previously been reported. In the present study, we …

The continuum of insulin development viewed in the context of a collaborative process toward leveraging science to save lives: following the trail of publications and …

A DeMarsilis, CS Mantzoros - Metabolism, 2022 - Elsevier
Nearly 100 years ago, diabetes, a disease expected to reach global prevalence of at least
10% within the decade, was a fatal diagnosis. This year of 2022 marks a century since …

[HTML][HTML] Multiple pretreatments can effectively improve the functionality of mesenchymal stem cells

XX Wan, XM Hu, K Xiong - World Journal of Stem Cells, 2024 - ncbi.nlm.nih.gov
In this editorial, we offer our perspective on the groundbreaking study entitled “Hypoxia and
inflammatory factor preconditioning enhances the immunosuppressive properties of human …

Global research trends of diabetes remission: a bibliometric study

X Yang, Z He, Q Chen, Y Chen, G Chen… - Frontiers in …, 2023 - frontiersin.org
Background Research on diabetes remission has garnered prominence in recent years.
However, to date, no pertinent bibliometric study has been published. This study sought to …

GFP tagged VSELs help delineate novel stem cells biology in multiple adult tissues

D Bhartiya, SA Mohammad, P Singh, D Sharma… - Stem Cell Reviews and …, 2022 - Springer
Various types of stem cells are being researched upon to exploit their potential for
regenerative medicine including pluripotent human embryonic stem (hES) cells derived from …

Effective generation of functional pancreatic β cells from human-derived dental stem cells of apical papilla and bone-marrow-derived stem cells: a comparative study

D Abuarqoub, S Adwan, R Zaza, S Wehaibi, N Aslam… - Pharmaceuticals, 2023 - mdpi.com
Diabetes Mellitus Type 1 is an autoimmune disease that occurs due to the destruction of
insulin-producing cells (β cells), resulting in hyperglycemia. Therefore, diabetic patients …