Bioinformatics approaches to discovering food-derived bioactive peptides: Reviews and perspectives

Z Du, J Comer, Y Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Food-derived bioactive peptides (FBPs) are gaining interest due to their great potential in
agricultural byproduct valorization and high-activity peptide screening. The introduction of …

Comprehensive evaluation and comparison of machine learning methods in QSAR modeling of antioxidant tripeptides

Z Du, D Wang, Y Li - ACS omega, 2022 - ACS Publications
Due to their multiple beneficial effects, antioxidant peptides have attracted increasing
interest. Currently, the screening and identification of bioactive peptides, including …

Improving depression prediction using a novel feature selection algorithm coupled with context-aware analysis

Z Dai, H Zhou, Q Ba, Y Zhou, L Wang, G Li - Journal of affective disorders, 2021 - Elsevier
Background: Developing machine learning based depression prediction method with
information from long-term recordings is important and challenging to clinical diagnosis of …

Maximal information coefficient and support vector regression based nonlinear feature selection and QSAR modeling on toxicity of alcohol compounds to tadpoles of …

L Wang, P Xing, C Wang, X Zhou, Z Dai… - Journal of the Brazilian …, 2019 - SciELO Brasil
Efficient evaluation of biotoxicity of organics is of vital significance to resource utilization and
environmental protection. In this study, toxicity of 110 alcohol compounds to tadpoles of …

Chi-MIC-share: A new feature selection algorithm for quantitative structure–activity relationship models

Y Li, Z Dai, D Cao, F Luo, Y Chen, Z Yuan - RSC advances, 2020 - pubs.rsc.org
Quantitative structure–activity relationship models are used in toxicology to predict the
effects of organic compounds on aquatic organisms. Common filter feature selection …

From Biomedicinal to In Silico Models and Back to Therapeutics: A Review on the Advancement of Peptidic Modeling

AS Moura, AK Halder… - Future Medicinal Chemistry, 2019 - Taylor & Francis
Bioactive peptides participate in numerous metabolic functions of living organisms and have
emerged as potential therapeutics on a diverse range of diseases. Albeit peptide design …

[PDF][PDF] 基于逐步非线性回归的血管紧张素转化酶抑制肽QSAR 建模

周恒, 巴庆芳, 袁哲明, 代志军 - 化学通报, 2022 - researchgate.net
摘要线性特征选择方法可提升定量构效关系(QSAR) 模型的预测能力, 但易忽略特征(理化属性)
与分子活性间的非线性关系. 本文提出基于支持向量回归(SVR) 的逐步非线性回归(SSNR) …

[PDF][PDF] SVR 算法的生物混液左旋多巴含量紫外光谱建模

王文哲 - 计算机与数字工程, 2022 - jsj.journal.cssc709.net
摘要以酪氨酸和左旋多巴混合溶液中左旋多巴的紫外光谱数据为研究对象, 首先用Kennard-
Stone 算法对样品集进行分割; 然后使用ν-SVR 和ε-SVR 算法对核进行建模, 以建立不同的核 …

[PDF][PDF] Statement of Research

KE YANG - cs.cmu.edu
I am a Ph. D. student in Computer Science at Carnegie Mellon University. I expect to
graduate on May of 2004. My research interests mainly lie in theoretical computer science …