Clinical translation of angiogenesis inhibitors

R Kerbel, J Folkman - Nature Reviews Cancer, 2002 - nature.com
Angiogenesis inhibitors are a new class of drugs, for which the general rules involving
conventional chemotherapy might not apply. The successful translation of angiogenesis …

Vascular anomalies

JB Mulliken, SJ Fishman, PE Burrows - Current problems in surgery, 2000 - Elsevier
This issue of Current Problems in Surgery is devoted to the topic of" Vascular Anomalies," a
clinical malady that is seen by almost all surgical specialists, but particularly by those who …

[HTML][HTML] Control of hair growth and follicle size by VEGF-mediated angiogenesis

K Yano, LF Brown, M Detmar - The Journal of clinical …, 2001 - Am Soc Clin Investig
The murine hair follicle undergoes pronounced cyclic expansion and regression, leading to
rapidly changing demands for its vascular support. Our study aimed to quantify the cyclic …

Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents

M Studeny, FC Marini, JL Dembinski… - Journal of the …, 2004 - academic.oup.com
Background: High concentrations of interferon beta (IFN-β) inhibit malignant cell growth in
vitro. However, the therapeutic utility of IFN-β in vivo is limited by its excessive toxicity when …

Propranolol for severe infantile hemangiomas: follow-up report

V Sans, ED de la Roque, J Berge, N Grenier… - …, 2009 - publications.aap.org
OBJECTIVE: Infantile hemangiomas (IHs) are the most-common soft-tissue tumors of
infancy. We report the use of propranolol to control the growth phase of IHs. METHODS …

[HTML][HTML] Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice

ZA Khan, E Boscolo, A Picard, S Psutka… - The Journal of …, 2008 - Am Soc Clin Investig
Infantile hemangioma is a benign endothelial tumor composed of disorganized blood
vessels. It exhibits a unique life cycle of rapid postnatal growth followed by slow regression …

Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses

R Salcedo, JJ Oppenheim - Microcirculation, 2003 - Taylor & Francis
Chemokines are small proteins that act as cell attractants via the activation of G protein-
coupled receptors. Chemokines play an important role in several pathophysiological …

Pathogenesis of infantile haemangioma

S Greenberger, J Bischoff - British Journal of Dermatology, 2013 - academic.oup.com
Haemangioma is a vascular tumour of infancy that is well known for its rapid growth during
the first weeks to months of a child's life, followed by a spontaneous but slow involution …

[图书][B] Color atlas of vascular tumors and vascular malformations

O Enjolras, M Wassef, R Chapot - 2007 - books.google.com
Hemangiomas and superficial vascular malformations are disfiguring birthmarks that can
occur over 65% of a child's body. This atlas will focus on the classification, multidisciplinary …

Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a

LB Kaban, JB Mulliken, RA Ezekowitz, D Phil… - …, 1999 - publications.aap.org
We report a 5-year-old girl with a large rapidly growing giant cell tumor of the mandible that
recurred 2 months after the first surgical excision and 3 months after a second resection. An …