Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents
In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …
Copper in tumors and the use of copper-based compounds in cancer treatment
DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …
The molecular mechanisms of copper metabolism and its roles in human diseases
J Chen, Y Jiang, H Shi, Y Peng, X Fan, C Li - Pflügers Archiv-European …, 2020 - Springer
Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …
electrons, participating in various reactions. However, an excess of copper ions in cells is …
Small-molecule two-photon probes for bioimaging applications
Small-molecule fluorescent probes are attractive and versatile materials for studying
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …
[HTML][HTML] Small heat shock proteins: role in cellular functions and pathology
Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
Copper induces microglia-mediated neuroinflammation through ROS/NF-κB pathway and mitophagy disorder
Q Zhou, Y Zhang, L Lu, H Zhang, C Zhao, Y Pu… - Food and Chemical …, 2022 - Elsevier
The epidemiological correlation between copper exposure and higher risk of Parkinson
disease (PD) has been recognized for a long time, and microglia-mediated …
disease (PD) has been recognized for a long time, and microglia-mediated …
[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Fluorescence “Turn-Off” and Colorimetric Sensor for Fe2+, Fe3+, and Cu2+ Ions Based on a 2,5,7-Triarylimidazopyridine Scaffold
S Sasan, T Chopra, A Gupta, D Tsering, KK Kapoor… - ACS …, 2022 - ACS Publications
Two cyanoimidazopyridine-based sensors (SS1 and SS2) were explored for the colorimetric
and fluorometric detection of Fe2+, Fe3+, and Cu2+ ions in the semi-aqueous medium. The …
and fluorometric detection of Fe2+, Fe3+, and Cu2+ ions in the semi-aqueous medium. The …
Fluoro-and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens
Heavy metal ions are of great concern, not only among the scientific community, especially
chemists, biologists, and environmentalists, but increasingly among the general population …
chemists, biologists, and environmentalists, but increasingly among the general population …