Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

AC Sedgwick, L Wu, HH Han, SD Bull, XP He… - Chemical Society …, 2018 - pubs.rsc.org
In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Copper in tumors and the use of copper-based compounds in cancer treatment

DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …

The molecular mechanisms of copper metabolism and its roles in human diseases

J Chen, Y Jiang, H Shi, Y Peng, X Fan, C Li - Pflügers Archiv-European …, 2020 - Springer
Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …

Small-molecule two-photon probes for bioimaging applications

HM Kim, BR Cho - Chemical reviews, 2015 - ACS Publications
Small-molecule fluorescent probes are attractive and versatile materials for studying
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …

[HTML][HTML] Small heat shock proteins: role in cellular functions and pathology

R Bakthisaran, R Tangirala, CM Rao - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …

Copper induces microglia-mediated neuroinflammation through ROS/NF-κB pathway and mitophagy disorder

Q Zhou, Y Zhang, L Lu, H Zhang, C Zhao, Y Pu… - Food and Chemical …, 2022 - Elsevier
The epidemiological correlation between copper exposure and higher risk of Parkinson
disease (PD) has been recognized for a long time, and microglia-mediated …

[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives

KD Fasae, AO Abolaji, TR Faloye, AY Odunsi… - Journal of Trace …, 2021 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …

Bioinorganic chemistry of Alzheimer's disease

KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Fluorescence “Turn-Off” and Colorimetric Sensor for Fe2+, Fe3+, and Cu2+ Ions Based on a 2,5,7-Triarylimidazopyridine Scaffold

S Sasan, T Chopra, A Gupta, D Tsering, KK Kapoor… - ACS …, 2022 - ACS Publications
Two cyanoimidazopyridine-based sensors (SS1 and SS2) were explored for the colorimetric
and fluorometric detection of Fe2+, Fe3+, and Cu2+ ions in the semi-aqueous medium. The …

Fluoro-and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens

DT Quang, JS Kim - Chemical reviews, 2010 - ACS Publications
Heavy metal ions are of great concern, not only among the scientific community, especially
chemists, biologists, and environmentalists, but increasingly among the general population …