Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Lipid droplets: packing hydrophobic molecules within the aqueous cytoplasm

A Guzha, P Whitehead, T Ischebeck… - Annual review of …, 2023 - annualreviews.org
Lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that
compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a …

Genome‐wide identification of EMBRYO‐DEFECTIVE (EMB) genes required for growth and development in Arabidopsis

DW Meinke - New Phytologist, 2020 - Wiley Online Library
With the emergence of high‐throughput methods in plant biology, the importance of long‐
term projects characterized by incremental advances involving multiple laboratories can …

Triacylglycerol Metabolism in Drosophila melanogaster

C Heier, RP Kühnlein - Genetics, 2018 - academic.oup.com
Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Flowers and climate change: a metabolic perspective

M Borghi, L Perez de Souza, T Yoshida… - New …, 2019 - Wiley Online Library
Adverse climatic conditions at the time of flowering severely hinder crop yields and threaten
the interactions between plants and their pollinators. These features depend on a common …

Lipid droplet biogenesis

CL Jackson - Current opinion in cell biology, 2019 - Elsevier
Lipid droplets (LDs) store neutral lipids in their core as an energy source when nutrients are
scarce. The center of an LD is hydrophobic, and hence it is surrounded by a phospholipid …

Metabolic engineering for enhanced oil in biomass

T Vanhercke, JM Dyer, RT Mullen, A Kilaru… - Progress in lipid …, 2019 - Elsevier
The world is hungry for energy. Plant oils in the form of triacylglycerol (TAG) are one of the
most reduced storage forms of carbon found in nature and hence represent an excellent …

Lipid droplets in plants and algae: Distribution, formation, turnover and function

T Ischebeck, HE Krawczyk, RT Mullen, JM Dyer… - Seminars in cell & …, 2020 - Elsevier
Plant oils represent an energy-rich and carbon-dense group of hydrophobic compounds.
These oils are not only of economic interest, but also play important, fundamental roles in …

Mechanisms of lipid droplet biogenesis

KD Chapman, M Aziz, JM Dyer… - Biochemical Journal, 2019 - portlandpress.com
Lipid droplets (LDs) are organelles that compartmentalize nonbilayer-forming lipids in the
aqueous cytoplasm of cells. They are ubiquitous in most organisms, including in animals …

Lipid droplets throughout the evolutionary tree

PK Lundquist, KK Shivaiah… - Progress in Lipid Research, 2020 - Elsevier
Intracellular lipid droplets are utilized for lipid storage and metabolism in organisms as
evolutionarily diverse as animals, fungi, plants, bacteria, and archaea. These lipid droplets …