Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Liver cirrhosis is an increasing public health threat worldwide. Malnutrition is a serious
complication of cirrhosis and is associated with worse outcomes. With this review, we aim to …

Our gut harbours trillions of microorganisms essential for the maintenance of homeostasis
and host physiology in health and disease. In the last decade, there has been a growing …

The gastrointestinal microbiota is emerging as a unique and inexhaustible source for
metabolites with potential to modulate G-protein coupled receptors (GPCRs). The ghrelin …

Background The human gut microbiota has emerged as a key factor in the development of
obesity. Certain probiotic strains have shown anti-obesity effects. The objective of this study …

Alcohol use disorder (AUD) is a leading cause of morbidity and mortality worldwide.
However, treatment options, including pharmacotherapies, are limited in number and …

The central amygdala (CeA) consists of numerous genetically defined inhibitory neurons
that control defensive and appetitive behaviors including feeding. Transcriptomic signatures …

Rodent studies indicate that ghrelin receptor blockade reduces alcohol consumption.
However, no ghrelin receptor blockers have been administered to heavy alcohol drinking …

Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …