Adenoviral vectors as vaccines for emerging avian influenza viruses
LJ Kerstetter, S Buckley, CM Bliss… - Frontiers in …, 2021 - frontiersin.org
It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …
More than just gene therapy vectors: Lentiviral vector pseudotypes for serological investigation
K Toon, EM Bentley, G Mattiuzzo - Viruses, 2021 - mdpi.com
Serological assays detecting neutralising antibodies are important for determining the
immune responses following infection or vaccination and are also often considered a …
immune responses following infection or vaccination and are also often considered a …
[PDF][PDF] A pan‐genotype hepatitis C virus viral vector vaccine generates T cells and neutralizing antibodies in mice
T Donnison, J McGregor, S Chinnakannan… - …, 2022 - Wiley Online Library
Background and Aims A prophylactic vaccine targeting multiple HCV genotypes (gt) is
urgently required to meet World Health Organization elimination targets. Neutralizing …
urgently required to meet World Health Organization elimination targets. Neutralizing …
The design and development of a multi-HBV antigen encoded in chimpanzee adenoviral and modified vaccinia Ankara viral vectors; a novel therapeutic vaccine …
Chronic hepatitis B virus (HBV) infection affects 257 million people globally. Current
therapies suppress HBV but viral rebound occurs on cessation of therapy; novel therapeutic …
therapies suppress HBV but viral rebound occurs on cessation of therapy; novel therapeutic …
[HTML][HTML] Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice
Seasonal influenza virus infections cause significant morbidity and mortality every year.
Annual influenza virus vaccines are effective but only when well matched with circulating …
Annual influenza virus vaccines are effective but only when well matched with circulating …
Integrase defective lentiviral vector as a vaccine platform for delivering influenza antigens
A Gallinaro, M Borghi, R Bona, F Grasso… - Frontiers in …, 2018 - frontiersin.org
Viral vectors represent an attractive technology for vaccine delivery. We exploited the
integrase defective lentiviral vector (IDLV) as a platform for delivering relevant antigens …
integrase defective lentiviral vector (IDLV) as a platform for delivering relevant antigens …
Heterologous combination of ChAdOx1 and MVA vectors expressing protein NS1 as vaccination strategy to induce durable and cross-protective CD8+ T cell immunity …
S Utrilla-Trigo, L Jiménez-Cabello, R Alonso-Ravelo… - Vaccines, 2020 - mdpi.com
The sequence of non-structural protein NS1 of bluetongue virus (BTV), which contains
immunodominant CD8+ T cell epitopes, is highly conserved among BTV serotypes, and has …
immunodominant CD8+ T cell epitopes, is highly conserved among BTV serotypes, and has …
Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse
A Flaxman, S Sebastian, S Appelberg, KM Cha… - PLoS …, 2024 - journals.plos.org
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years,
VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial …
VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial …
Universal influenza virus vaccines: what needs to happen next?
C Trucchi, C Paganino, D Amicizia, A Orsi… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Influenza occurs worldwide and causes significant disease burden in terms of
morbidity, associated complications, hospitalizations, and deaths. Vaccination constitutes …
morbidity, associated complications, hospitalizations, and deaths. Vaccination constitutes …
The Combined Expression of the Nonstructural Protein NS1 and the N-Terminal Half of NS2 (NS21-180) by ChAdOx1 and MVA Confers Protection against Clinical …
S Utrilla-Trigo, L Jiménez-Cabello… - Journal of …, 2022 - Am Soc Microbiol
Bluetongue, caused by bluetongue virus (BTV), is a widespread arthropod-borne disease of
ruminants that entails a recurrent threat to the primary sector of developed and developing …
ruminants that entails a recurrent threat to the primary sector of developed and developing …