The function of the RNA-binding protein hnRNP in cancer metastasis

N Han, W Li, M Zhang - Journal of cancer research and …, 2013 - journals.lww.com
Heterogeneous ribonucleoproteins (hnRNPs) are involved in a variety of key cellular
functions and are most likely involved in different steps of pre-mRNA processing. Over the …

What did we learn from multiple omics studies in asthma?

O Ivanova, LB Richards, SJ Vijverberg, AH Neerincx… - Allergy, 2019 - Wiley Online Library
More than a decade has passed since the finalization of the Human Genome Project. Omics
technologies made a huge leap from trendy and very expensive to routinely executed and …

Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific

T Wang, Y Cui, J Jin, J Guo, G Wang, X Yin… - Nucleic acids …, 2013 - academic.oup.com
As a well-known phenomenon, total mRNAs poorly correlate to proteins in their abundances
as reported. Recent findings calculated with bivariate models suggested even poorer such …

Advanced maternal age‐associated SIRT1 deficiency compromises trophoblast epithelial− mesenchymal transition through an increase in vimentin acetylation

L Xiong, X Ye, Z Chen, H Fu, S Li, P Xu, J Yu… - Aging cell, 2021 - Wiley Online Library
Advanced maternal age (AMA) pregnancies are rapidly increasing and are associated with
aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes …

Abnormal expression of EMT-related proteins, S100A4, vimentin and E-cadherin, is correlated with clinicopathological features and prognosis in HCC

X Zhai, H Zhu, W Wang, S Zhang, Y Zhang, G Mao - Medical oncology, 2014 - Springer
We determined the expression of epithelial-mesenchymal transition (EMT) indicator
proteins, E-cadherin (E-cad), vimentin (VIM), mucin 1 (MUC1) and S100 calcium-binding …

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Y Wang, J Zhang, ZH Huang, XH Huang… - Cell death & …, 2017 - nature.com
Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to
exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells …

FoxQ1 overexpression influences poor prognosis in non-small cell lung cancer, associates with the phenomenon of EMT

J Feng, X Zhang, H Zhu, X Wang, S Ni, J Huang - PloS one, 2012 - journals.plos.org
Background We determined the expression of forkhead box Q1 (FoxQ1), E-cadherin (E-cad),
Mucin 1 (MUC1), vimentin (VIM) and S100 calcium binding protein A4 (S100A4), all …

[HTML][HTML] Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages

Z Chen, L Yang, Y Cui, Y Zhou, X Yin, J Guo, G Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The exosome is a key initiator of pre-metastatic niche in numerous cancers, where
macrophages serve as primary inducers of tumor microenvironment. However, the proteome …

Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF …

Y Huang, Z Li, E Lin, P He, G Ru - Experimental & Molecular Medicine, 2021 - nature.com
In vitro fertilization (IVF) increases the risk of tumorigenesis in offspring. The increased
oxidative damage during IVF may be involved in tumor formation. However, the molecular …

Overexpression of FOXM1 is associated with EMT and is a predictor of poor prognosis in non-small cell lung cancer

FF Kong, ZQ Qu, HH Yuan, JY Wang… - Oncology …, 2014 - spandidos-publications.com
Abstract Forkhead box M1 (FOXM1), a member of the Fox family of transcriptional factors, is
considered to be an independent predictor of poor survival in many solid cancers. However …