Nitric oxide (NO) is a free radical gas that has been shown to be produced by nitric oxide
synthase (NOS) in different cell types and recognized to act as a neurotransmitter or …

Trigeminal autonomic cephalalgias (TACs) are discrete primary headache disorders,
characterized by severe unilateral head pain, typically trigeminal distribution, with ipsilateral …

Nonsteroidal anti-inflammatory drugs, cyclooxygenase inhibitors, are used routinely in the
treatment of primary headache disorders. Indomethacin is unique in its use in the diagnosis …

Objective To determine whether activation of transient receptor potential vanilloid 4 (TRPV‐
4) induces inflammation in the rat temporomandibular joint (TMJ), and to assess the effects …

Aims. To establish a new model of zymosan‐induced temporomandibular joint (TMJ) arthritis
in the rat and to investigate the role of nitric oxide. Methods. Inflammation was induced by an …

Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide
area in the orofacial region. Its exact mechanism remains unclear. We investigated the …

Background Nerve injury may induce neuropathic pain. In studying the mechanisms of
orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the …

Background Previous data showed that, in rats, anti‐migraine drugs (triptans, olcegepant)
significantly reduced mechanical allodynia induced by infraorbital nerve (ION) ligation but …

Nitric oxide (NO) is a soluble gas that participates in important functions of the central
nervous system, such as cognitive function, maintenance of synaptic plasticity for the control …

This study investigated the antinociceptive and anti-inflammatory effects of
electroacupuncture (EA) on zymosan-induced acute arthritis of the rat temporomandibular …