Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity—a review of literature evidence

AC Famurewa, MY George, CA Ukwubile, S Kumar… - BioMetals, 2024 - Springer
Anticancer chemotherapy (ACT) remains a cornerstone in cancer treatment, despite
significant advances in pharmacology over recent decades. However, its associated side …

Ameliorative effect of herbacetin against cyclophosphamide-induced nephrotoxicity in rats via attenuation of oxidative stress, inflammation, apoptosis and …

MU Ijaz, S Mustafa, R Batool, H Naz… - Human & …, 2022 - journals.sagepub.com
Herbacetin (HBN) is a glycosylated flavonoid, which possesses numerous pharmacological
properties. Cyclophosphamide (CYC) is a chemotherapeutic drug that adversely affects the …

Apigetrin ameliorates doxorubicin prompted testicular damage: biochemical, spermatological and histological based study

MU Ijaz, S Yaqoob, A Hamza, M David, T Afsar… - Scientific Reports, 2024 - nature.com
Doxorubicin (DOX) is a highly effective, commonly prescribed, potent anti-neoplastic drug
that damages the testicular tissues and leads to infertility. Apigetrin (APG) is an important …

[HTML][HTML] Gossypetin mitigates doxorubicin-induced nephrotoxicity: A histopathological and biochemical evaluation

MU Ijaz, K Alvi, HA Khan, M Imran, T Afsar… - Journal of King Saud …, 2023 - Elsevier
Doxorubicin (DOX) is an anticancer agent that is generally used to treat wide range of
malignancies. Gossypetin (GTIN) is a well-known bioflavonoid that shows multiple …

Co-administration of thymol and sulfoxaflor impedes the expression of reproductive toxicity in male rats

AS Tijani, TM Daba, IA Ubong, O Olufunke… - Drug and Chemical …, 2024 - Taylor & Francis
This study investigated the capability of a co-delivery system of thymol (THY) and sulfoxaflor
that can serve to minimize the development of epididymal and testicular injury arise from …

Protective effect of Chlorella vulgaris on testicular damage, sperm parameters, androgen production, apoptosis and oxidative stress index in male rats following …

A Makipour, S Hosseinifar, K Khazaeel… - Reproductive …, 2024 - Elsevier
Doxorubicin (DOX) is a chemotherapy agent associated with adverse effects on male
reproductive health. Chlorella vulgaris (ChV) is a potent natural antioxidant with promising …

Thymol co-administration abrogates hexachlorobenzene-induced reproductive toxicities in male rats

AS Tijani, EO Farombi, DO Olori - Human & Experimental …, 2023 - journals.sagepub.com
This present study was designed to investigate ameliorating potential of thymol (THY) on
hexachlorobenzene (HBC)-induced epididymal and testicular toxicities in adult male rats …

Iridoid glycoside Aucubin protects against nonylphenol-induced testicular damage in male rats via modulation of steroidogenic and apoptotic signaling

IUL Hassan, N Ehsan, MU Ijaz, T Afsar, H Amor… - Scientific Reports, 2022 - nature.com
Aucubin (AU) is one of the widespread compounds belonging to the group of iridoid
glycosides, which possesses numerous beneficial properties. Nonylphenol (NP), is a …

Protective effects of diosmin on doxorubicin-induced testicular toxicity in rat

A Malayeri, SM Birgani, Z Basir, H Kalantar - … -Schmiedeberg's Archives of …, 2024 - Springer
Doxorubicin (DOX) can be applied to treat several cancers. DOX-induced oxidative stress
causes testicular damage. Diosmin (DIO), as a potent antioxidant, reduces many drugs' side …

[HTML][HTML] Evaluation of possible protective role of glabridin against gentamicin-instigated nephrotoxicity via attenuation of oxidative stress

MU Ijaz, S Mustafa, A Hamza, BO Almutairi… - Journal of King Saud …, 2023 - Elsevier
Glabridin (GB) is a natural dietary flavonoid of plant origin with excellent antioxidant
properties. Gentamicin (GM) is an aminoglycoside antibiotic that can potentially cause renal …